HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: GGA1 (Q9UJY5)
ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	17494868, 14660606, 15143060, 38803224, 19285159
Identification Methods	pull down, two hybrid, affinity chromatography technology, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	GAT~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0010008 - endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 639
+	Hs
		476481 UBC_HUMAN (1-685): 0: 846: 100.00		GGA3_HUMAN (6-639): 3.76e-158: 473: 48.47
+	Hs
		241137 UBC_HUMAN (1-685): 0: 846: 100.00		TOM1_HUMAN (7-467): 2.18e-108: 337: 22.62
+	Hs
		475949 UBC_HUMAN (1-685): 0: 846: 100.00		TM1L2_HUMAN (7-473): 1.61e-98: 312: 21.66
+	Hs
		276993 UBC_HUMAN (1-685): 0: 846: 100.00		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		476138 UBC_HUMAN (1-685): 0: 846: 100.00		STAM1_HUMAN (3-519): 4.73e-90: 291: 16.05
+	Hs
		159860 UBC_HUMAN (1-685): 0: 846: 100.00		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Bt
		477668 UBC_BOVIN (1-613): 0: 753: 99.18		Q58CQ6_BOVIN (1-420): 4.99e-115: 352: 78.30
+	Hs
		272789 UBC_HUMAN (1-685): 0: 846: 100.00		TM1L1_HUMAN (7-461): 2.07e-74: 248: 19.23
+	Zm
		111864 Q42415_MAIZE (229-685): 0: 548: 95.84		K7VAA4_MAIZE (37-631): 8.38e-89: 296: 16.31
+	Zm
		111863 Q41754_MAIZE (381-685): 3.03e-124: 375: 95.74		K7VAA4_MAIZE (37-631): 8.38e-89: 296: 16.31
+	Sc
		477270 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		GGA2_YEAST (2-633): 2.86e-93: 301: 20.71
+	Sc
		477454 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		GGA1_YEAST (2-440): 7.58e-79: 262: 20.79
+	At
		1091731 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		AP1G1_ARATH (28-631): 7.27e-82: 278: 15.36
+	At
		285943 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		TOL6_ARATH (15-384): 1.91e-65: 229: 17.66
+	Mm
		292209 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TOM1_MOUSE (7-474): 4.47e-109: 339: 23.08
+	Hs
		277047 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Mm
		476811 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		TM1L2_MOUSE (7-474): 1.5e-99: 315: 22.02
+	Hs
		924099 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		STAM1_HUMAN (3-519): 4.73e-90: 291: 16.05
+	Mm
		292343 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		STAM2_MOUSE (3-518): 1.02e-96: 308: 14.56
+	Mm
		476756 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		STAM1_MOUSE (3-535): 2.79e-90: 292: 16.67