HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.97	1.00	0.986

Property	Details
Experiments	25416956, 25752573, 30659753, 31699778, 38803224, 16196087, 15147878, 22428841, 23823328, 23649778, 28075048, 31175912, 24361330, 16007098, 15004330, 19798103
Identification Methods	two hybrid, pull down, unspecified method, affinity chromatography technology, x-ray crystallography, surface plasmon resonance
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 589
+	Hs
		476525 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		476438 UBC_HUMAN (1-685): 0: 846: 100.00		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Xl
		1186353 Q7SY79_XENLA (77-685): 0: 744: 99.84		Q9PVN8_XENLA (16-589): 3.64e-137: 413: 57.71
+	Hs
		476101 UBC_HUMAN (1-685): 0: 846: 100.00		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		475888 UBC_HUMAN (1-685): 0: 846: 100.00		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		475591 UBC_HUMAN (1-685): 0: 846: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Dm
		477540 UBIQP_DROME (1-610): 0: 752: 99.84		Q9VXF9_DROME (37-317): 4.08e-51: 184: 17.93
+	Hs
		475590 UBC_HUMAN (1-685): 0: 846: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		1286323 Q96C32_HUMAN (229-533): 1.87e-118: 358: 99.67		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Dm
		1375397 Q9W418_DROME (229-685): 0: 557: 99.78		Q9VXF9_DROME (37-317): 4.08e-51: 184: 17.93
+	Dm
		574862 Q9W418_DROME (229-685): 0: 557: 99.78		RL40_DROME (37-126): 7.82e-34: 126: 29.67
+	Hs
		924208 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Pf
		1181547 Q7KQK2_PLAF7 (381-685): 3.65e-126: 380: 98.36		Q8IJS8_PLAF7 (37-351): 6.06e-38: 146: 15.30
+	At
		1247032 RUB2_ARATH (457-608): 1.43e-47: 166: 78.29		DSK2A_ARATH (19-586): 8.36e-108: 336: 32.87
+	Sc
		477189 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73
+	Sc
		477360 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		DSK2_YEAST (36-243): 8.16e-32: 128: 30.73
+	At
		1091781 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		Q8L745_ARATH (23-139): 2.76e-12: 71.8: 23.73
+	Hs
		923945 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Bt
		924446 RS27A_BOVIN (609-684): 7.23e-41: 148: 100.00		RS27A_BOVIN (37-123): 8.94e-26: 105: 30.68
+	Hs
		923944 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68