HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	11146632, 16307917, 18042044
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 303
+	Hs
		213459 UBC_HUMAN (1-685): 0: 846: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Pf
		1181548 Q7KQK2_PLAF7 (381-685): 3.65e-126: 380: 98.36		HSOP_PLAF7 (25-276): 1.95e-17: 84.3: 16.60
+	Mm
		924235 RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00		PPP5_MOUSE (1-259): 7.23e-36: 136: 20.91
+	Hs
		213522 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Rn
		1144220 UBC_RAT (1-108): 1.27e-29: 127: 90.74		TOM70_RAT (2-212): 1.69e-38: 144: 22.07
+	Rn
		251113 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SGTA_RAT (3-140): 5.31e-33: 125: 28.99
+	Rn
		1144228 UBC_RAT (1-108): 1.27e-29: 127: 90.74		SGTB_RAT (70-177): 2.28e-09: 59.3: 18.52