HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP24 (Q9UPU5)
Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24)
Gene: USP24

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.917

Property	Details
Experiments	28190767, 29576527, 33141564, 34642328, 36114200
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 2620
+	Hs
		131635 UBC_HUMAN (1-685): 0: 846: 100.00		USP9Y_HUMAN (70-2593): 0: 2602: 28.97
+	Hs
		476146 UBC_HUMAN (1-685): 0: 846: 100.00		USP9X_HUMAN (70-2593): 0: 2576: 28.76
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (1671-2568): 0: 614: 18.11
+	Hs
		475952 UBC_HUMAN (1-685): 0: 846: 100.00		UBP34_HUMAN (554-1226): 7.46e-161: 561: 20.11
+	Hs
		476147 UBC_HUMAN (1-685): 0: 846: 100.00		UBP7_HUMAN (1527-2308): 5.52e-138: 465: 17.12
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (1597-2184): 1.17e-114: 377: 18.20
+	Hs
		476213 UBC_HUMAN (1-685): 0: 846: 100.00		UBP47_HUMAN (1593-2079): 7.81e-103: 366: 20.72
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (1519-2044): 1.65e-103: 348: 17.16
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (1634-2042): 3.95e-103: 344: 20.18
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (1619-2035): 1.96e-102: 338: 19.87
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (1687-2043): 8.06e-100: 328: 23.24
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (1688-2043): 7.32e-99: 325: 23.56
+	Hs
		476452 UBC_HUMAN (1-685): 0: 846: 100.00		UBP40_HUMAN (1677-1977): 1.42e-25: 118: 28.12
+	Mm
		476669 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		UBP48_MOUSE (1671-2568): 0: 589: 17.36
+	At
		1210479 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP15_ARATH (1594-2218): 2.61e-107: 369: 16.92
+	Sc
		477365 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP15_YEAST (1669-2086): 1.57e-98: 350: 22.66
+	At
		1092066 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP12_ARATH (1616-2392): 1.33e-126: 432: 18.25
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (1616-2258): 1.31e-125: 428: 20.24
+	At
		1092065 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP15_ARATH (1594-2218): 2.61e-107: 369: 16.92
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (1677-2009): 6.42e-24: 110: 27.25