HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP20 (Q9Y2K6)
Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2) (hVDU2)
Gene: USP20

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.755

Property	Details
Experiments	29576527, 31278784
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	DUSP~ubiquitin, UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 914
+	Hs
		476097 UBC_HUMAN (1-685): 0: 846: 100.00		UBP33_HUMAN (1-914): 0: 803: 57.96
+	Hs
		475693 UBC_HUMAN (1-685): 0: 846: 100.00		UBP4_HUMAN (105-715): 1.25e-110: 365: 18.14
+	Hs
		476644 UBC_HUMAN (1-685): 0: 846: 100.00		UBP16_HUMAN (4-684): 2.16e-106: 350: 17.74
+	Hs
		475957 UBC_HUMAN (1-685): 0: 846: 100.00		UBP45_HUMAN (7-684): 1.07e-99: 331: 18.25
+	Hs
		475954 UBC_HUMAN (1-685): 0: 846: 100.00		UBP31_HUMAN (144-720): 2.34e-87: 306: 18.14
+	Hs
		296262 UBC_HUMAN (1-685): 0: 846: 100.00		UBP1_HUMAN (98-649): 2.08e-78: 273: 17.68
+	Hs
		476529 UBC_HUMAN (1-685): 0: 846: 100.00		UBP25_HUMAN (128-818): 2.76e-71: 257: 12.71
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (420-693): 7.77e-67: 234: 31.05
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (240-688): 4.25e-56: 204: 18.52
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (96-271): 1.55e-47: 181: 27.22
+	Hs
		301354 UBC_HUMAN (1-685): 0: 846: 100.00		UBP19_HUMAN (85-409): 1.12e-43: 174: 18.21
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (112-450): 2.18e-46: 174: 16.38
+	Hs
		476545 UBC_HUMAN (1-685): 0: 846: 100.00		UBP21_HUMAN (101-267): 5.83e-38: 152: 28.98
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (79-452): 8.19e-35: 142: 11.91
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (77-553): 9.06e-33: 139: 12.60
+	Hs
		476624 UBC_HUMAN (1-685): 0: 846: 100.00		UBP15_HUMAN (132-247): 4.24e-18: 91.7: 41.80
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (15-255): 1.44e-46: 176: 25.20
+	Hs
		475502 UBC_HUMAN (1-685): 0: 846: 100.00		UBP11_HUMAN (135-247): 5.22e-15: 81.6: 39.17
+	Hs
		475440 UBC_HUMAN (1-685): 0: 846: 100.00		UBP8_HUMAN (143-249): 1.16e-11: 70.9: 37.17
+	Hs
		476067 UBC_HUMAN (1-685): 0: 846: 100.00		UBP32_HUMAN (424-483): 2.35e-10: 66.7: 31.67