HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	27182664, 31518855
Identification Methods	proximity labelling technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 318
+	Hs
		475586 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		476604 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		475501 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		475550 UBC_HUMAN (1-685): 0: 846: 100.00		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		475504 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30
+	Hs
		476040 UBC_HUMAN (1-685): 0: 846: 100.00		UB2J2_HUMAN (1-150): 3.16e-63: 202: 39.87
+	Hs
		476155 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E3_HUMAN (2-156): 9.16e-63: 199: 26.58
+	Hs
		476218 UBC_HUMAN (1-685): 0: 846: 100.00		UB2E2_HUMAN (2-156): 2.19e-62: 198: 27.22
+	Hs
		475485 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2A_HUMAN (7-154): 3.69e-61: 193: 21.85
+	Hs
		475597 UBC_HUMAN (1-685): 0: 846: 100.00		UBE2B_HUMAN (7-154): 6.08e-60: 190: 22.52
+	Hs
		475543 UBC_HUMAN (1-685): 0: 846: 100.00		UB2G2_HUMAN (7-142): 5.84e-58: 185: 26.00
+	Hs
		475573 UBC_HUMAN (1-685): 0: 846: 100.00		UB2G1_HUMAN (15-148): 2.26e-56: 182: 25.83
+	Xl
		919927 Q7SY79_XENLA (77-685): 0: 744: 99.84		UB2D2_XENLA (10-156): 5.15e-70: 216: 28.00
+	Dm
		639414 Q9W418_DROME (229-685): 0: 557: 99.78		UBCD1_DROME (10-156): 3.06e-69: 214: 29.33
+	Sc
		477103 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC4_YEAST (9-156): 2.23e-66: 206: 25.83
+	Sc
		477198 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBC6_YEAST (9-148): 3.01e-61: 197: 39.72
+	At
		715116 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC8_ARATH (10-156): 9.73e-68: 210: 29.33
+	At
		715132 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC9_ARATH (10-156): 3.55e-67: 208: 29.33
+	At
		715147 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC10_ARATH (10-156): 4.86e-67: 208: 28.67
+	At
		639385 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBC1_ARATH (7-154): 2.63e-60: 191: 21.19