HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RN114 (Q9Y508)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: RNF114

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

Property	Details
Experiments	30659753, 18364390, 38803224, 16196087, 19285159
Identification Methods	pull down, unspecified method, affinity chromatography technology, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 228
+	Hs
		476160 UBC_HUMAN (1-685): 0: 846: 100.00		RN166_HUMAN (2-227): 1.03e-58: 187: 40.69
+	Hs
		476111 UBC_HUMAN (1-685): 0: 846: 100.00		RN138_HUMAN (17-225): 7.06e-49: 161: 31.09
+	Hs
		476188 UBC_HUMAN (1-685): 0: 846: 100.00		RN125_HUMAN (2-227): 2.29e-48: 160: 30.84
+	Hs
		475680 UBC_HUMAN (1-685): 0: 846: 100.00		TRI26_HUMAN (15-162): 1.14e-29: 117: 16.88
+	Hs
		475328 UBC_HUMAN (1-685): 0: 846: 100.00		RO52_HUMAN (15-134): 8.35e-26: 106: 18.98
+	Hs
		476627 UBC_HUMAN (1-685): 0: 846: 100.00		TRAF6_HUMAN (19-179): 6.78e-26: 106: 20.48
+	Hs
		129527 UBC_HUMAN (1-685): 0: 846: 100.00		TRAF5_HUMAN (24-174): 2.07e-25: 105: 20.63
+	Hs
		476489 UBC_HUMAN (1-685): 0: 846: 100.00		KCMF1_HUMAN (49-220): 6.38e-26: 105: 22.29
+	Hs
		476418 UBC_HUMAN (1-685): 0: 846: 100.00		TRI39_HUMAN (1-150): 1.11e-23: 100: 19.28
+	Hs
		476330 UBC_HUMAN (1-685): 0: 846: 100.00		TRIM5_HUMAN (16-222): 1.94e-23: 99.6: 17.11
+	Hs
		475309 UBC_HUMAN (1-685): 0: 846: 100.00		RAG1_HUMAN (23-122): 1.3e-22: 97.6: 20.95
+	Hs
		475753 UBC_HUMAN (1-685): 0: 846: 100.00		TRI25_HUMAN (18-176): 2.8e-22: 96.4: 17.84
+	Xl
		1186351 Q7SY79_XENLA (77-685): 0: 744: 99.84		NF7B_XENLA (3-154): 6.3e-28: 112: 15.29
+	Mm
		476671 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		RO52_MOUSE (11-135): 1.23e-25: 105: 14.79
+	At
		1092004 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		SM3L1_ARATH (14-73): 5.3e-18: 84: 31.67
+	Mm
		476977 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RN138_MOUSE (12-225): 4.99e-48: 160: 30.04
+	Hs
		924227 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRAF6_HUMAN (19-179): 6.78e-26: 106: 20.48
+	Mm
		924236 RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00		RO52_MOUSE (11-135): 1.23e-25: 105: 14.79
+	Hs
		923989 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		TRI25_HUMAN (18-176): 2.8e-22: 96.4: 17.84
+	Mm
		476831 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		RO52_MOUSE (11-135): 1.23e-25: 105: 14.79