HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: AP2A1 (P17426)
AP-2 complex subunit alpha-1 (100 kDa coated vesicle protein A) (Adaptor protein complex AP-2 subunit alpha-1) (Adaptor-related protein complex 2 subunit alpha-1) (Alpha-adaptin A) (Alpha1-adaptin) (Clathrin assembly protein complex 2 alpha-A large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit)
Gene: AP2A1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 977
+	Mm
		476684 UBC_MOUSE (1-734): 0: 912: 100.00		AP2A2_MOUSE (1-977): 0: 847: 77.69
+	Rn
		1144175 UBC_RAT (1-724): 0: 898: 97.51		Q66HM2_RAT (1-977): 0: 851: 77.69
+	Hs
		321470 UBC_HUMAN (77-724): 0: 790: 97.22		AP2A1_HUMAN (1-977): 0: 909: 97.75
+	Hs
		302094 UBC_HUMAN (77-724): 0: 790: 97.22		AP2A2_HUMAN (1-977): 0: 839: 77.28
+	Mm
		477012 UBC_MOUSE (1-734): 0: 912: 100.00		AP2B1_MOUSE (36-972): 0: 693: 16.89
+	Rn
		923858 UBC_RAT (1-724): 0: 898: 97.51		AP2B1_RAT (36-972): 0: 692: 16.89
+	Hs
		475594 UBC_HUMAN (77-724): 0: 790: 97.22		AP2B1_HUMAN (36-972): 0: 692: 16.89
+	Zm
		111864 Q42415_MAIZE (229-724): 0: 592: 92.54		K7VAA4_MAIZE (3-852): 0: 592: 23.92
+	At
		1091811 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		AP2A2_ARATH (8-977): 0: 735: 36.71
+	Hs
		321462 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		AP2A1_HUMAN (1-977): 0: 909: 97.75
+	Zm
		111863 Q41754_MAIZE (381-724): 8.3e-139: 414: 90.99		K7VAA4_MAIZE (3-852): 0: 592: 23.92
+	Hs
		302089 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		AP2A2_HUMAN (1-977): 0: 839: 77.28
+	At
		286688 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		APBLC_ARATH (36-973): 0: 631: 14.96
+	At
		1092397 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		APBLB_ARATH (36-973): 0: 618: 15.17
+	At
		1091731 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		AP1G1_ARATH (1-853): 0: 575: 23.21
+	At
		1013363 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		COPG_ARATH (29-974): 0: 556: 14.17
+	At
		1091782 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		AP4E_ARATH (11-739): 1.36e-171: 527: 21.06
+	Hs
		397894 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		AP2B1_HUMAN (36-972): 0: 692: 16.89
+	Hs
		924203 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		COPG2_HUMAN (18-969): 3.02e-179: 544: 13.90