HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: FAF1 (P54731)
FAS-associated factor 1
Gene: FAF1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UBA_4~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 649
+	Rn
		1144247 UBC_RAT (1-724): 0: 898: 97.51		FAF1_RAT (1-649): 0: 846: 98.61
+	Hs
		476571 UBC_HUMAN (77-724): 0: 790: 97.22		FAF1_HUMAN (1-649): 0: 862: 96.15
+	Mm
		476842 UBC_MOUSE (1-734): 0: 912: 100.00		UBXN7_MOUSE (329-648): 6.34e-73: 244: 17.94
+	Mm
		476779 UBC_MOUSE (1-734): 0: 912: 100.00		FAF2_MOUSE (319-648): 4.32e-69: 233: 22.86
+	Mm
		476957 UBC_MOUSE (1-734): 0: 912: 100.00		UBXN1_MOUSE (413-648): 3.46e-36: 139: 18.40
+	Hs
		299310 UBC_HUMAN (77-724): 0: 790: 97.22		UBXN7_HUMAN (329-648): 1.87e-71: 241: 17.94
+	Hs
		476174 UBC_HUMAN (77-724): 0: 790: 97.22		FAF2_HUMAN (319-648): 1.82e-69: 234: 22.86
+	Hs
		398140 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		FAF1_HUMAN (1-649): 0: 862: 96.15
+	Hs
		475246 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		FAF1_HUMAN (1-649): 0: 862: 96.15
+	Hs
		475650 UBC_HUMAN (77-724): 0: 790: 97.22		UBXN1_HUMAN (413-648): 2.1e-33: 131: 18.00
+	Hs
		476575 UBC_HUMAN (77-724): 0: 790: 97.22		NSF1C_HUMAN (411-648): 2.69e-12: 70.6: 13.69
+	Sc
		477464 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		UBX5_YEAST (335-644): 7.09e-45: 169: 11.36
+	Sc
		477438 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		UBX2_YEAST (357-648): 2.71e-42: 163: 12.95
+	Hs
		299309 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		UBXN7_HUMAN (329-648): 1.87e-71: 241: 17.94
+	Hs
		475128 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		FAF2_HUMAN (319-648): 1.82e-69: 234: 22.86
+	Hs
		397924 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		UBXN1_HUMAN (413-648): 2.1e-33: 131: 18.00
+	Hs
		398141 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		NSF1C_HUMAN (411-648): 2.69e-12: 70.6: 13.69