HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: UCHL4 (P58321)
Ubiquitin carboxyl-terminal hydrolase isozyme L4 (UCH-L4) (EC 3.4.19.12) (Ubiquitin thioesterase L4)
Gene: UCHL4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 233
+	Mm
		477030 UBC_MOUSE (1-734): 0: 912: 100.00		UCHL3_MOUSE (1-233): 1.91e-108: 313: 95.28
+	Mm
		477056 UBC_MOUSE (1-734): 0: 912: 100.00		UCHL5_MOUSE (6-231): 2.44e-92: 276: 28.14
+	Mm
		477047 UBC_MOUSE (1-734): 0: 912: 100.00		UCHL1_MOUSE (8-233): 5.85e-85: 253: 53.10
+	Rn
		962731 UBC_RAT (1-724): 0: 898: 97.51		UCHL1_RAT (8-233): 5.85e-85: 253: 53.10
+	Hs
		475307 UBC_HUMAN (77-724): 0: 790: 97.22		UCHL3_HUMAN (1-233): 1.85e-108: 313: 94.42
+	Hs
		476639 UBC_HUMAN (77-724): 0: 790: 97.22		UCHL5_HUMAN (1-231): 3.78e-92: 275: 28.57
+	Hs
		456475 UBC_HUMAN (77-724): 0: 790: 97.22		UCHL1_HUMAN (8-233): 5.21e-87: 258: 54.43
+	Hs
		476130 UBC_HUMAN (77-724): 0: 790: 97.22		BAP1_HUMAN (3-231): 3.58e-79: 253: 22.13
+	Sc
		477215 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		UBL1_YEAST (2-230): 2.28e-51: 168: 31.12
+	Hs
		474910 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		UCHL3_HUMAN (1-233): 1.85e-108: 313: 94.42
+	Hs
		548107 Q5U5U6_HUMAN (1-77): 3.45e-27: 112: 98.70		UCHL3_HUMAN (1-233): 1.85e-108: 313: 94.42
+	Hs
		456536 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		UCHL1_HUMAN (8-233): 5.21e-87: 258: 54.43
+	Hs
		924096 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		BAP1_HUMAN (3-231): 3.58e-79: 253: 22.13
+	Hs
		398154 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		UCHL5_HUMAN (1-231): 3.78e-92: 275: 28.57
+	Hs
		456474 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		UCHL1_HUMAN (8-233): 5.21e-87: 258: 54.43