HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: TAB3 (Q571K4)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.696

Property	Details
Experiments	28190767, 19136968
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CUE~ubiquitin
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 716
+	Hs
		476046 UBC_HUMAN (77-724): 0: 790: 97.22		TAB3_HUMAN (1-716): 1.45e-113: 360: 94.83
+	Mm
		476964 UBC_MOUSE (1-734): 0: 912: 100.00		TAB2_MOUSE (1-715): 3.29e-63: 225: 30.86
+	Rn
		1144063 UBC_RAT (1-724): 0: 898: 97.51		SYNJ1_RAT (2-585): 6.04e-60: 221: 12.13
+	Hs
		476477 UBC_HUMAN (77-724): 0: 790: 97.22		TAB2_HUMAN (1-715): 1.97e-74: 256: 30.86
+	Hs
		475943 UBC_HUMAN (77-724): 0: 790: 97.22		OTOG_HUMAN (180-547): 3.03e-13: 75.9: 12.60
+	Hs
		302245 UBC_HUMAN (77-724): 0: 790: 97.22		SC31A_HUMAN (78-415): 3.92e-11: 68.6: 15.07
+	At
		1092229 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		SC24C_ARATH (154-505): 1.59e-10: 66.7: 13.22
+	At
		1092118 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		Q9LIE8_ARATH (238-580): 2.78e-10: 65.9: 12.54
+	Hs
		398114 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		TAB2_HUMAN (1-715): 1.97e-74: 256: 30.86
+	Hs
		475212 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		TAB2_HUMAN (1-715): 1.97e-74: 256: 30.86
+	Hs
		397925 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		IF4G1_HUMAN (72-555): 1.29e-10: 67.1: 9.34