HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: TRAF4 (Q61382)
TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich motif associated to RING and Traf domains protein 1)
Gene: TRAF4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 470
+	Rn
		78208 UBC_RAT (1-724): 0: 898: 97.51		B5DFH7_RAT (2-465): 3.58e-94: 295: 28.23
+	Hs
		476299 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF4_HUMAN (1-470): 2.59e-135: 400: 96.81
+	Rn
		88507 UBC_RAT (1-724): 0: 898: 97.51		D3Z9G0_RAT (3-465): 1.02e-81: 265: 24.12
+	Hs
		476627 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF6_HUMAN (3-464): 3.53e-98: 306: 24.79
+	Hs
		475684 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF2_HUMAN (2-465): 6.94e-96: 299: 28.46
+	Mm
		476831 UBC_MOUSE (1-734): 0: 912: 100.00		RO52_MOUSE (4-249): 6.4e-42: 157: 15.14
+	Hs
		129527 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF5_HUMAN (2-465): 5.84e-81: 262: 26.21
+	Hs
		475691 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF1_HUMAN (2-465): 8.41e-72: 234: 22.53
+	Hs
		475328 UBC_HUMAN (77-724): 0: 790: 97.22		RO52_HUMAN (9-289): 1.55e-41: 155: 14.54
+	Hs
		476418 UBC_HUMAN (77-724): 0: 790: 97.22		TRI39_HUMAN (9-302): 1.75e-38: 148: 14.91
+	Hs
		475842 UBC_HUMAN (77-724): 0: 790: 97.22		RN151_HUMAN (3-163): 2.26e-39: 144: 26.38
+	Hs
		476160 UBC_HUMAN (77-724): 0: 790: 97.22		RN166_HUMAN (12-146): 7.91e-16: 78.8: 26.47
+	Mm
		476671 UBB_MOUSE (457-724): 3.16e-101: 315: 93.28		RO52_MOUSE (4-249): 6.4e-42: 157: 15.14
+	Hs
		924227 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		TRAF6_HUMAN (3-464): 3.53e-98: 306: 24.79
+	Hs
		397944 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		TRAF2_HUMAN (2-465): 6.94e-96: 299: 28.46
+	Hs
		475011 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		TRAF2_HUMAN (2-465): 6.94e-96: 299: 28.46
+	At
		1091851 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		Q8W1E7_ARATH (80-231): 2.32e-11: 68: 24.18
+	Hs
		301744 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		TRI37_HUMAN (5-465): 5.55e-63: 222: 14.90
+	Mm
		924236 RS27A_MOUSE (609-684): 4.05e-42: 152: 100.00		RO52_MOUSE (4-249): 6.4e-42: 157: 15.14
+	Hs
		924180 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		ZNF71_HUMAN (85-306): 1.28e-31: 128: 14.22