HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: UBP8 (Q80U87)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: Usp8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	24533902, 16810319
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 1080
+	Hs
		475440 UBC_HUMAN (77-724): 0: 790: 97.22		UBP8_HUMAN (1-1080): 0: 679: 80.86
+	Mm
		476939 UBC_MOUSE (1-734): 0: 912: 100.00		UBP3_MOUSE (737-1075): 1.16e-109: 353: 32.60
+	Mm
		476741 UBC_MOUSE (1-734): 0: 912: 100.00		UBP46_MOUSE (729-1071): 2.02e-109: 347: 26.94
+	Mm
		477008 UBC_MOUSE (1-734): 0: 912: 100.00		UBP12_MOUSE (701-1072): 8.85e-109: 345: 25.71
+	Rn
		1137288 UBC_RAT (1-724): 0: 898: 97.51		UBP2_RAT (507-1073): 2.27e-109: 356: 26.49
+	Mm
		476898 UBC_MOUSE (1-734): 0: 912: 100.00		UBP44_MOUSE (559-1071): 7.21e-90: 306: 20.97
+	Dm
		477538 UBIQP_DROME (1-686): 0: 873: 99.85		NOT_DROME (731-1070): 3.01e-104: 337: 28.74
+	Hs
		271022 UBC_HUMAN (77-724): 0: 790: 97.22		UBP2_HUMAN (678-1073): 1.79e-113: 366: 36.66
+	Hs
		475566 UBC_HUMAN (77-724): 0: 790: 97.22		UBP46_HUMAN (729-1071): 2.02e-109: 347: 26.94
+	Hs
		259261 UBC_HUMAN (77-724): 0: 790: 97.22		UBP12_HUMAN (701-1072): 2.62e-107: 341: 25.71
+	Hs
		64200 UBC_HUMAN (77-724): 0: 790: 97.22		UBP27_HUMAN (707-1080): 3.02e-105: 338: 25.24
+	Mm
		476793 UBC_MOUSE (1-734): 0: 912: 100.00		UBP19_MOUSE (924-1072): 2.52e-45: 180: 39.24
+	Mm
		476926 UBC_MOUSE (1-734): 0: 912: 100.00		UBP15_MOUSE (926-1068): 1.09e-34: 145: 49.65
+	Mm
		476963 UBC_MOUSE (1-734): 0: 912: 100.00		UBP11_MOUSE (922-1068): 4.07e-34: 143: 45.03
+	Mm
		476695 UBC_MOUSE (1-734): 0: 912: 100.00		UBP4_MOUSE (903-1068): 7.58e-32: 136: 39.52
+	Rn
		70290 UBC_RAT (1-724): 0: 898: 97.51		UBP4_RAT (926-1068): 1.93e-31: 135: 43.36
+	Mm
		101489 UBC_MOUSE (1-734): 0: 912: 100.00		UBP32_MOUSE (919-1004): 1.25e-14: 81.3: 42.53
+	Hs
		475502 UBC_HUMAN (77-724): 0: 790: 97.22		UBP11_HUMAN (926-1068): 8.78e-34: 142: 44.90
+	Hs
		301354 UBC_HUMAN (77-724): 0: 790: 97.22		UBP19_HUMAN (925-1068): 3.84e-27: 121: 43.14
+	Hs
		475403 UBC_HUMAN (77-724): 0: 790: 97.22		UBP6_HUMAN (919-1004): 8.91e-11: 68.6: 37.21