HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: EPN1 (Q80VP1)
Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1)
Gene: EPN1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	28190767, 29676259
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 575
+	Rn
		291394 UBC_RAT (1-724): 0: 898: 97.51		EPN1_RAT (1-575): 3.47e-111: 345: 99.13
+	Mm
		476910 UBC_MOUSE (1-734): 0: 912: 100.00		EPN2_MOUSE (1-556): 3.09e-81: 267: 40.69
+	Hs
		476657 UBC_HUMAN (77-724): 0: 790: 97.22		EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79
+	Dm
		477525 UBIQP_DROME (1-686): 0: 873: 99.85		Q7KU90_DROME (1-574): 7.2e-62: 220: 30.12
+	Hs
		307500 UBC_HUMAN (77-724): 0: 790: 97.22		EPN2_HUMAN (1-570): 9.04e-74: 249: 39.37
+	Hs
		476358 UBC_HUMAN (77-724): 0: 790: 97.22		EPN3_HUMAN (1-570): 4.86e-67: 230: 40.71
+	Hs
		475943 UBC_HUMAN (77-724): 0: 790: 97.22		OTOG_HUMAN (155-543): 5.04e-16: 84.2: 10.35
+	Sc
		477505 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		ENT1_YEAST (3-192): 2.51e-70: 235: 37.90
+	Sc
		477449 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		ENT2_YEAST (3-537): 4.89e-68: 233: 19.04
+	Dm
		1182371 R9PY16_DROME (457-724): 5.16e-94: 296: 85.82		Q7KU90_DROME (1-574): 7.2e-62: 220: 30.12
+	At
		1091714 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		EPN2_ARATH (2-573): 1.12e-54: 200: 20.82
+	Hs
		924231 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		EPN1_HUMAN (1-575): 1.37e-105: 331: 94.79
+	Hs
		111209 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		I6L9I8_HUMAN (1-290): 3.77e-105: 321: 52.83
+	Hs
		397968 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		EPN4_HUMAN (3-557): 1.3e-93: 301: 24.40
+	Hs
		307522 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		EPN2_HUMAN (1-570): 9.04e-74: 249: 39.37
+	Hs
		924159 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		EPN3_HUMAN (1-570): 4.86e-67: 230: 40.71
+	Hs
		475183 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		EPN3_HUMAN (1-570): 4.86e-67: 230: 40.71