HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: VPS36 (Q91XD6)
Vacuolar protein-sorting-associated protein 36 (ESCRT-II complex subunit VPS36)
Gene: VPS36

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	28190767, 17057714
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Vps36_ESCRT-II~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 386
+	Rn
		69934 UBC_RAT (1-724): 0: 898: 97.51		B1H248_RAT (1-386): 0: 513: 98.45
+	Hs
		476000 UBC_HUMAN (77-724): 0: 790: 97.22		VPS36_HUMAN (1-386): 6.15e-178: 501: 95.86
+	Mm
		476990 UBC_MOUSE (1-734): 0: 912: 100.00		SNF8_MOUSE (152-382): 5.35e-76: 237: 21.31
+	Hs
		476200 UBC_HUMAN (77-724): 0: 790: 97.22		SNF8_HUMAN (152-382): 5.41e-76: 237: 21.31
+	Sc
		477465 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		VPS36_YEAST (136-382): 5.61e-64: 215: 17.63
+	Hs
		475084 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		VPS36_HUMAN (1-386): 6.15e-178: 501: 95.86