HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: RNF31 (Q924T7)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31)
Gene: RNF31

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	28190767, 29676259
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E3_UbLigase_RBR~ubiquitin, IBR~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 1066
+	Hs
		476187 UBC_HUMAN (77-724): 0: 790: 97.22		RNF31_HUMAN (1-1066): 0: 1126: 86.47
+	Dm
		477528 UBIQP_DROME (1-686): 0: 873: 99.85		LUBEL_DROME (203-647): 3.02e-79: 287: 16.67
+	Mm
		476729 UBC_MOUSE (1-734): 0: 912: 100.00		RN216_MOUSE (589-997): 1.8e-67: 245: 13.58
+	Hs
		476630 UBC_HUMAN (77-724): 0: 790: 97.22		ARI1_HUMAN (594-1052): 2.79e-114: 366: 15.09
+	Hs
		312458 UBC_HUMAN (77-724): 0: 790: 97.22		ARI2_HUMAN (585-1028): 1.82e-99: 325: 14.97
+	Hs
		476496 UBC_HUMAN (77-724): 0: 790: 97.22		AKIB1_HUMAN (425-1034): 2.51e-70: 257: 12.03
+	Mm
		476855 UBC_MOUSE (1-734): 0: 912: 100.00		ZRAN1_MOUSE (202-383): 1.44e-28: 125: 18.72
+	Hs
		476460 UBC_HUMAN (77-724): 0: 790: 97.22		RN216_HUMAN (589-998): 5.3e-65: 238: 14.22
+	Hs
		475939 UBC_HUMAN (77-724): 0: 790: 97.22		RN19B_HUMAN (692-975): 6.43e-62: 227: 21.64
+	Hs
		475976 UBC_HUMAN (77-724): 0: 790: 97.22		R144B_HUMAN (673-920): 1.92e-60: 210: 20.62
+	Hs
		475494 UBC_HUMAN (77-724): 0: 790: 97.22		R144A_HUMAN (693-899): 7.03e-58: 203: 23.61
+	Hs
		476517 UBC_HUMAN (77-724): 0: 790: 97.22		ZRAN1_HUMAN (202-363): 1.94e-28: 124: 18.24
+	Dm
		1214032 Q9W418_DROME (1-458): 0: 588: 99.56		LUBEL_DROME (203-647): 3.02e-79: 287: 16.67
+	Dm
		1367032 Q9W418_DROME (1-458): 0: 588: 99.56		TRBID_DROME (231-607): 3.19e-63: 232: 12.70
+	Dr
		48762 F1QHN6_DANRE (229-724): 0: 602: 96.37		ZRN1B_DANRE (151-343): 2.8e-32: 137: 17.50
+	Sc
		477225 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		HEL1_YEAST (623-1036): 2.84e-85: 288: 15.35
+	Hs
		312457 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		ARI2_HUMAN (585-1028): 1.82e-99: 325: 14.97
+	Hs
		475094 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		CUL9_HUMAN (638-1053): 7.11e-82: 295: 16.86
+	Hs
		475069 UBB_HUMAN (1-77): 3.45e-27: 112: 98.70		RN19B_HUMAN (692-975): 6.43e-62: 227: 21.64
+	Hs
		924207 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		ZRAN1_HUMAN (202-363): 1.94e-28: 124: 18.24