HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: HGS (Q99LI8)
Hepatocyte growth factor-regulated tyrosine kinase substrate
Gene: HGS

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.80	0.752

Property	Details
Experiments	28190767, 29676259, 17182860
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	VHS~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 775
+	Rn
		1144280 UBC_RAT (1-724): 0: 898: 97.51		HGS_RAT (1-775): 4.36e-135: 420: 97.29
+	Hs
		159860 UBC_HUMAN (77-724): 0: 790: 97.22		HGS_HUMAN (1-775): 6.25e-136: 422: 93.31
+	Dm
		477530 UBIQP_DROME (1-686): 0: 873: 99.85		HRS_DROME (6-640): 3.68e-73: 255: 41.28
+	Mm
		292209 UBC_MOUSE (1-734): 0: 912: 100.00		TOM1_MOUSE (5-143): 5.49e-43: 165: 35.66
+	Mm
		476811 UBC_MOUSE (1-734): 0: 912: 100.00		TM1L2_MOUSE (5-162): 8.75e-43: 164: 33.33
+	Mm
		69089 UBC_MOUSE (1-734): 0: 912: 100.00		A8Y5G5_MOUSE (133-482): 1.44e-40: 163: 15.73
+	Mm
		476756 UBC_MOUSE (1-734): 0: 912: 100.00		STAM1_MOUSE (4-158): 8.19e-41: 159: 31.61
+	Mm
		292343 UBC_MOUSE (1-734): 0: 912: 100.00		STAM2_MOUSE (4-155): 1.39e-38: 152: 32.24
+	Rn
		78185 UBC_RAT (1-724): 0: 898: 97.51		B5DF55_RAT (4-158): 2.65e-41: 161: 31.61
+	Mm
		476884 UBC_MOUSE (1-734): 0: 912: 100.00		GGA3_MOUSE (7-146): 1.71e-32: 136: 28.97
+	Hs
		475982 UBC_HUMAN (77-724): 0: 790: 97.22		FGD2_HUMAN (3-346): 1.7e-44: 172: 12.50
+	Hs
		475975 UBC_HUMAN (77-724): 0: 790: 97.22		ZFY16_HUMAN (152-477): 5.36e-41: 164: 18.09
+	Hs
		476138 UBC_HUMAN (77-724): 0: 790: 97.22		STAM1_HUMAN (4-158): 6.1e-41: 160: 30.97
+	Hs
		313490 UBC_HUMAN (77-724): 0: 790: 97.22		ZFYV9_HUMAN (133-477): 1.34e-37: 153: 18.31
+	Hs
		276993 UBC_HUMAN (77-724): 0: 790: 97.22		STAM2_HUMAN (4-556): 1.17e-37: 150: 14.85
+	Hs
		475949 UBC_HUMAN (77-724): 0: 790: 97.22		TM1L2_HUMAN (5-164): 7.38e-38: 150: 31.10
+	Hs
		476481 UBC_HUMAN (77-724): 0: 790: 97.22		GGA3_HUMAN (7-146): 1.37e-35: 146: 29.66
+	Hs
		241137 UBC_HUMAN (77-724): 0: 790: 97.22		TOM1_HUMAN (5-158): 1.69e-35: 143: 31.65
+	Hs
		476499 UBC_HUMAN (77-724): 0: 790: 97.22		ANFY1_HUMAN (156-219): 1.74e-14: 79.7: 50.00
+	Sc
		477270 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		GGA2_YEAST (6-539): 5.17e-40: 158: 14.13