HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: RN138 (Q9CQE0)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: Rnf138

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	28190767, 36800290
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_2
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 245
+	Mm
		476831 UBC_MOUSE (1-734): 0: 912: 100.00		RO52_MOUSE (8-157): 7.08e-29: 115: 11.80
+	Mm
		476826 UBC_MOUSE (1-734): 0: 912: 100.00		TRAF4_MOUSE (8-207): 1.89e-24: 102: 14.35
+	Rn
		88507 UBC_RAT (1-724): 0: 898: 97.51		D3Z9G0_RAT (8-245): 6.08e-29: 115: 14.64
+	Rn
		78208 UBC_RAT (1-724): 0: 898: 97.51		B5DFH7_RAT (2-239): 4.79e-27: 110: 11.42
+	Hs
		476111 UBC_HUMAN (77-724): 0: 790: 97.22		RN138_HUMAN (1-245): 2.45e-59: 189: 93.88
+	Hs
		476160 UBC_HUMAN (77-724): 0: 790: 97.22		RN166_HUMAN (5-244): 5.2e-42: 144: 31.12
+	Hs
		476627 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF6_HUMAN (8-245): 3.04e-36: 135: 14.98
+	Hs
		476632 UBC_HUMAN (77-724): 0: 790: 97.22		RN114_HUMAN (15-241): 3.2e-38: 134: 31.72
+	Hs
		476188 UBC_HUMAN (77-724): 0: 790: 97.22		RN125_HUMAN (2-245): 1.66e-36: 130: 27.05
+	Hs
		129527 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF5_HUMAN (8-245): 6.54e-33: 127: 15.90
+	Hs
		476254 UBC_HUMAN (77-724): 0: 790: 97.22		RING2_HUMAN (2-188): 1.96e-34: 127: 19.15
+	Hs
		475680 UBC_HUMAN (77-724): 0: 790: 97.22		TRI26_HUMAN (3-184): 3.17e-31: 122: 17.16
+	Hs
		475328 UBC_HUMAN (77-724): 0: 790: 97.22		RO52_HUMAN (3-151): 5.44e-31: 120: 14.38
+	Hs
		476330 UBC_HUMAN (77-724): 0: 790: 97.22		TRIM5_HUMAN (5-178): 5.2e-30: 118: 14.74
+	Hs
		476418 UBC_HUMAN (77-724): 0: 790: 97.22		TRI39_HUMAN (9-181): 6.63e-30: 118: 18.18
+	Hs
		475309 UBC_HUMAN (77-724): 0: 790: 97.22		RAG1_HUMAN (8-110): 2.73e-29: 117: 24.27
+	Hs
		476635 UBC_HUMAN (77-724): 0: 790: 97.22		TRI17_HUMAN (3-177): 8.14e-28: 112: 13.47
+	Hs
		476299 UBC_HUMAN (77-724): 0: 790: 97.22		TRAF4_HUMAN (8-207): 6.83e-25: 103: 14.35
+	Hs
		476489 UBC_HUMAN (77-724): 0: 790: 97.22		KCMF1_HUMAN (146-236): 5.44e-24: 100: 31.87
+	Hs
		475658 UBC_HUMAN (77-724): 0: 790: 97.22		RING1_HUMAN (2-74): 1.79e-21: 93.8: 28.77