HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: AP2B1 (Q9DBG3)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 734 Mm			1 937
+	Rn
		923858 UBC_RAT (1-724): 0: 898: 97.51		AP2B1_RAT (1-937): 0: 924: 99.89
+	Hs
		475594 UBC_HUMAN (77-724): 0: 790: 97.22		AP2B1_HUMAN (1-937): 0: 924: 99.89
+	Mm
		476683 UBC_MOUSE (1-734): 0: 912: 100.00		AP2A1_MOUSE (11-932): 0: 633: 16.94
+	Mm
		476684 UBC_MOUSE (1-734): 0: 912: 100.00		AP2A2_MOUSE (11-932): 0: 600: 16.29
+	Rn
		1144175 UBC_RAT (1-724): 0: 898: 97.51		Q66HM2_RAT (11-932): 0: 595: 16.17
+	Hs
		321470 UBC_HUMAN (77-724): 0: 790: 97.22		AP2A1_HUMAN (11-932): 0: 634: 16.77
+	Hs
		302094 UBC_HUMAN (77-724): 0: 790: 97.22		AP2A2_HUMAN (11-933): 0: 604: 16.89
+	Hs
		475514 UBC_HUMAN (77-724): 0: 790: 97.22		COPB_HUMAN (8-927): 0: 567: 12.88
+	Zm
		111864 Q42415_MAIZE (229-724): 0: 592: 92.54		K7VAA4_MAIZE (13-808): 1.92e-180: 546: 15.95
+	At
		286688 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		APBLC_ARATH (3-936): 0: 758: 56.46
+	At
		1092397 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		APBLB_ARATH (3-936): 0: 754: 56.14
+	Zm
		111863 Q41754_MAIZE (381-724): 8.3e-139: 414: 90.99		K7VAA4_MAIZE (13-808): 1.92e-180: 546: 15.95
+	At
		1092398 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		COPB1_ARATH (6-919): 0: 575: 13.74
+	At
		1091811 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		AP2A2_ARATH (13-934): 0: 556: 15.95
+	At
		1091731 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		AP1G1_ARATH (14-809): 3.18e-174: 530: 16.34
+	At
		1013363 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		COPG_ARATH (3-933): 4.47e-173: 527: 13.94
+	At
		1092096 UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55		APBLA_ARATH (12-741): 2.61e-165: 506: 30.62
+	Hs
		321462 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		AP2A1_HUMAN (11-932): 0: 634: 16.77
+	Hs
		302089 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		AP2A2_HUMAN (11-933): 0: 604: 16.89
+	Hs
		863195 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		COPB_HUMAN (8-927): 0: 567: 12.88