HitPredict

Interactor 1: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Interactor 2: AMFR (Q9R049)
E3 ubiquitin-protein ligase AMFR (EC 2.3.2.36) (Autocrine motility factor receptor) (AMF receptor) (RING-type E3 ubiquitin transferase AMFR)
Gene: AMFR

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CUE~ubiquitin, ubiquitin~zf-RING_2
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 734 Mm			1 643
+	Hs
		476551 UBC_HUMAN (77-724): 0: 790: 97.22		AMFR_HUMAN (1-643): 0: 613: 94.40
+	Rn
		1140402 UBC_RAT (1-724): 0: 898: 97.51		MGRN1_RAT (303-619): 1.37e-56: 202: 18.87
+	Mm
		476784 UBC_MOUSE (1-734): 0: 912: 100.00		CBLB_MOUSE (293-600): 1.11e-34: 142: 16.86
+	Rn
		88778 UBC_RAT (1-724): 0: 898: 97.51		D3ZV15_RAT (293-619): 2.01e-37: 151: 17.61
+	Mm
		476994 UBC_MOUSE (1-734): 0: 912: 100.00		RN115_MOUSE (316-400): 3.17e-24: 105: 29.21
+	Hs
		476224 UBC_HUMAN (77-724): 0: 790: 97.22		RN145_HUMAN (80-470): 7.92e-55: 199: 15.92
+	Hs
		475339 UBC_HUMAN (77-724): 0: 790: 97.22		CBL_HUMAN (293-619): 8.94e-34: 140: 16.48
+	Hs
		475700 UBC_HUMAN (77-724): 0: 790: 97.22		CBLB_HUMAN (293-600): 3.22e-32: 135: 15.94
+	Hs
		476628 UBC_HUMAN (77-724): 0: 790: 97.22		RN115_HUMAN (316-400): 5.49e-24: 104: 28.09
+	Hs
		924212 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		AMFR_HUMAN (1-643): 0: 613: 94.40
+	Sc
		477469 UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99		HRD1_YEAST (74-398): 5.37e-46: 173: 15.91
+	Hs
		610336 RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00		CBL_HUMAN (293-619): 8.94e-34: 140: 16.48
+	Hs
		398150 ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69		RN115_HUMAN (316-400): 5.49e-24: 104: 28.09