HitPredict

Interactor 1: S12A8 (A0AV02)
Solute carrier family 12 member 8 (Cation-chloride cotransporter 9)
Gene: SLC12A8

Interactor 2: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 714 Hs			1 404
+	Hs
		849636 S12A5_HUMAN (12-421): 5.41e-131: 417: 22.39		CCR4_HUMAN (22-371): 3.06e-72: 232: 22.88
+	Hs
		172150 YLAT2_HUMAN (8-477): 5.24e-104: 329: 15.39		GP182_HUMAN (1-404): 1.17e-85: 268: 100.00
+	Hs
		1031070 S12A9_HUMAN (38-420): 4.77e-108: 351: 27.21		GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72
+	Hs
		723286 S12A2_HUMAN (8-447): 1.53e-99: 333: 29.57		APJ_HUMAN (34-397): 3.04e-72: 232: 23.48
+	Hs
		171941 CTR1_HUMAN (8-409): 1.9e-85: 283: 14.61		GP182_HUMAN (1-404): 1.17e-85: 268: 100.00
+	Hs
		171962 CTR2_HUMAN (2-451): 6.1e-85: 283: 13.76		GP182_HUMAN (1-404): 1.17e-85: 268: 100.00
+	Hs
		781037 S12A7_HUMAN (34-421): 2.8e-89: 303: 22.02		OPRD_HUMAN (9-376): 2.45e-74: 237: 21.43
+	Hs
		854868 CTR2_HUMAN (2-451): 6.1e-85: 283: 13.76		CXCR4_HUMAN (25-343): 3.18e-72: 231: 22.36
+	Hs
		854883 CTR2_HUMAN (2-451): 6.1e-85: 283: 13.76		GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72
+	Hs
		134363 CTR1_HUMAN (8-409): 1.9e-85: 283: 14.61		ACKR2_HUMAN (43-331): 2.65e-32: 127: 33.33
+	Hs
		598928 CTR2_HUMAN (2-451): 6.1e-85: 283: 13.76		FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28
+	Hs
		626506 CTR2_HUMAN (2-451): 6.1e-85: 283: 13.76		FPR2_HUMAN (53-346): 7.4e-23: 100: 26.33