HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: RAD18 (P10862)
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)
Gene: RAD18

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	19396164, 38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 381 Sc			1 487
+	Mm
		476831 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		RO52_MOUSE (12-400): 1.36e-88: 280: 12.29
+	Mm
		476671 UBB_MOUSE (77-380): 7.87e-127: 368: 96.05		RO52_MOUSE (12-400): 1.36e-88: 280: 12.29
+	Mm
		477039 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		RAD18_MOUSE (16-457): 1.86e-63: 216: 21.43
+	Hs
		475134 UBB_HUMAN (77-304): 5.9e-91: 274: 96.05		TRI11_HUMAN (21-392): 8.05e-74: 242: 12.50
+	Hs
		475177 UBB_HUMAN (77-304): 5.9e-91: 274: 96.05		TRIM5_HUMAN (14-392): 4.06e-71: 235: 10.99
+	Xl
		1186351 Q7SY79_XENLA (1-229): 7.03e-88: 279: 95.63		NF7B_XENLA (8-430): 8.2e-63: 216: 10.15
+	Hs
		475205 UBB_HUMAN (77-304): 5.9e-91: 274: 96.05		RAD18_HUMAN (16-437): 6.5e-61: 209: 20.73
+	Hs
		475328 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		RO52_HUMAN (15-392): 1.57e-94: 296: 12.38
+	Hs
		476418 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43
+	Hs
		475297 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		TRI27_HUMAN (15-391): 1.4e-73: 243: 9.09
+	Hs
		476330 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		TRIM5_HUMAN (14-392): 4.06e-71: 235: 10.99
+	Hs
		476635 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		TRI17_HUMAN (14-433): 1.42e-69: 231: 10.43
+	Hs
		476443 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		RAD18_HUMAN (16-437): 6.5e-61: 209: 20.73
+	Mm
		924236 RS27A_MOUSE (77-153): 8.69e-20: 87: 94.81		RO52_MOUSE (12-400): 1.36e-88: 280: 12.29
+	Hs
		475680 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		TRI26_HUMAN (15-334): 1.92e-51: 184: 11.94
+	Hs
		475753 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19
+	Hs
		476078 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		COP1_HUMAN (16-349): 2.62e-36: 144: 16.27
+	Hs
		397963 ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68		TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19
+	Hs
		923989 RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81		TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19
+	Hs
		924151 RS27A_HUMAN (77-153): 8.44e-20: 87: 94.81		TRI31_HUMAN (21-323): 3.03e-35: 137: 11.82