HitPredict

Interactor 1: HSP77 (P0CS90)
Import motor subunit, mitochondrial (EC 3.6.4.10) (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70)
Gene: SSC1

Interactor 2: YPK1 (P12688)
Serine/threonine-protein kinase YPK1 (EC 2.7.11.1) (Sphingosine-like immunosuppressant resistant protein 2) (Yeast protein kinase 1)
Gene: YPK1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	25792736, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 654 Sc			1 680
+	Sc
		579938 HSP7E_YEAST (17-646): 0: 969: 82.22		YPK2_YEAST (1-679): 0: 607: 67.34
+	Sc
		477878 HSP77_YEAST (1-654): 0: 896: 100.00		YPK2_YEAST (1-679): 0: 607: 67.34
+	Hs
		564016 HSP76_HUMAN (27-651): 0: 863: 47.42		AKT1_HUMAN (203-666): 6.7e-164: 481: 34.75
+	Hs
		503528 HSP7C_HUMAN (28-634): 0: 861: 48.87		AKT1_HUMAN (203-666): 6.7e-164: 481: 34.75
+	Hs
		503390 HSP7C_HUMAN (28-634): 0: 861: 48.87		KPCA_HUMAN (196-668): 3.1e-157: 471: 30.04
+	Hs
		503922 HSP7C_HUMAN (28-634): 0: 861: 48.87		KPCE_HUMAN (265-669): 3.09e-150: 455: 36.25
+	Mm
		554912 HS71A_MOUSE (28-654): 0: 854: 46.67		KPCE_MOUSE (265-669): 7.16e-151: 456: 35.77
+	Hs
		564201 HSP76_HUMAN (27-651): 0: 863: 47.42		KS6B2_HUMAN (303-671): 8.42e-150: 445: 42.40
+	Hs
		504896 HSP7C_HUMAN (28-634): 0: 861: 48.87		KS6B2_HUMAN (303-671): 8.42e-150: 445: 42.40
+	Hs
		681702 GRP75_HUMAN (16-654): 0: 788: 64.90		AKT1_HUMAN (203-666): 6.7e-164: 481: 34.75
+	Dm
		669847 HSP7E_DROME (3-644): 0: 757: 62.36		AKT1_DROME (117-669): 1.4e-160: 477: 30.07
+	Hs
		751869 GRP75_HUMAN (16-654): 0: 788: 64.90		KS6B2_HUMAN (303-671): 8.42e-150: 445: 42.40
+	Hs
		564041 HSP76_HUMAN (27-651): 0: 863: 47.42		KS6A3_HUMAN (338-610): 1.3e-88: 294: 30.53
+	Hs
		503719 HSP7C_HUMAN (28-634): 0: 861: 48.87		KS6A3_HUMAN (338-610): 1.3e-88: 294: 30.53
+	Hs
		751545 GRP75_HUMAN (16-654): 0: 788: 64.90		KS6A3_HUMAN (338-610): 1.3e-88: 294: 30.53
+	Hs
		501740 BIP_HUMAN (30-632): 0: 542: 50.82		AKT1_HUMAN (203-666): 6.7e-164: 481: 34.75
+	Mm
		554943 Q9DC41_MOUSE (30-632): 0: 542: 50.82		KPCE_MOUSE (265-669): 7.16e-151: 456: 35.77
+	Hs
		502638 BIP_HUMAN (30-632): 0: 542: 50.82		KS6B2_HUMAN (303-671): 8.42e-150: 445: 42.40
+	Hs
		501852 BIP_HUMAN (30-632): 0: 542: 50.82		KS6A3_HUMAN (338-610): 1.3e-88: 294: 30.53