HitPredict

Interactor 1: TM129 (A0AVI4)
E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129)
Gene: TMEM129

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 25030448, 24807418, 31289263
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006986 - response to unfolded protein
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 362
Hs

1 251
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024