HitPredict

Interactor 1: UBA6 (A0AVT1)
Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (EC 6.2.1.45) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)
Gene: UBA6

Interactor 2: UBE2T (Q9NPD8)
Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T)
Gene: UBE2T

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17597759
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006974 - DNA damage response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 197
+	Hs
		48104 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D1_HUMAN (2-152): 1.05e-76: 228: 41.72
+	Hs
		48107 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D2_HUMAN (2-152): 1.52e-76: 227: 41.72
+	Hs
		48106 UBA6_HUMAN (1-1052): 0: 1156: 100.00		UB2D3_HUMAN (2-152): 2.48e-75: 224: 41.06
+	Hs
		607190 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D4_HUMAN (2-152): 1.11e-77: 230: 39.74
+	Hs
		607026 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D1_HUMAN (2-152): 1.05e-76: 228: 41.72
+	Hs
		607050 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D2_HUMAN (2-152): 1.52e-76: 227: 41.72
+	Hs
		607169 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2T_HUMAN (1-197): 8.53e-76: 227: 100.00
+	Hs
		607039 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2D3_HUMAN (2-152): 2.48e-75: 224: 41.06
+	Hs
		607042 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2N_HUMAN (4-152): 1.1e-70: 213: 44.97
+	Hs
		607136 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2E2_HUMAN (3-152): 6.78e-69: 210: 40.00
+	Hs
		607129 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2E3_HUMAN (3-152): 1.45e-68: 209: 40.00
+	Hs
		607028 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UB2E1_HUMAN (3-152): 1.27e-67: 206: 40.00
+	Hs
		607023 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2A_HUMAN (3-149): 1.89e-66: 202: 34.01
+	Hs
		607054 UBA1_HUMAN (1-1045): 0: 1139: 40.92		UBE2B_HUMAN (3-149): 1.12e-65: 200: 34.69
+	Sp
		293848 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC4_SCHPO (2-151): 1.57e-75: 225: 42.00
+	Sc
		549788 UBA1_YEAST (24-1046): 0: 979: 40.52		UBC4_YEAST (1-151): 3.03e-76: 227: 41.72
+	Dm
		715098 Q8T0L3_DROME (21-1045): 0: 990: 40.89		UBE2N_DROME (2-151): 4.3e-66: 201: 46.67
+	Sc
		608714 UBA1_YEAST (24-1046): 0: 979: 40.52		UBC13_YEAST (2-156): 4.53e-69: 208: 43.87
+	Sp
		142467 UBA1_SCHPO (26-1043): 0: 995: 40.25		UBC13_SCHPO (1-151): 1.19e-38: 131: 45.70
+	Hs
		782203 UBA7_HUMAN (34-1045): 0: 905: 36.34		UB2E1_HUMAN (3-152): 1.27e-67: 206: 40.00