HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 23791178, 24847877
Identification Methods anti tag coimmunoprecipitation, x-ray crystallography, ion mobility mass spectrometry of complexes
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C2~C2, C2~SMP_LBD, SMP_LBD~SMP_LBD
Common GO terms GO:0005509 - calcium ion binding
GO:0005544 - calcium-dependent phospholipid binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 12 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 921
Hs

1 921
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024