Interactor 1: MTAL2 (P0CY08)
Mating-type protein ALPHA2 (MATalpha2 protein) (Alpha-2 repressor)
Gene: MATALPHA2

Interactor 2: MCM1 (P11746)
Pheromone receptor transcription factor (GRM/PRTF protein)
Gene: MCM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 8628280, 9490409
Identification Methods anti tag coimmunoprecipitation, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~SRF-TF
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 210
Sc

1 286
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024