HitPredict

Interactor 1: TPC2A (P0DI81)
Trafficking protein particle complex subunit 2 (Sedlin)
Gene: TRAPPC2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044325 - transmembrane transporter binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 245
+	Hs
		483241 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		483301 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		483288 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		483243 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		483303 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		483234 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		483290 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		483244 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		483306 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		483240 TPC2A_HUMAN (1-140): 8.79e-67: 200: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		483300 TPC2B_HUMAN (1-140): 8.79e-67: 200: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33