HitPredict

Interactor 1: RGPD2 (P0DJD1)
RANBP2-like and GRIP domain-containing protein 2 (Ran-binding protein 2-like 2) (RanBP2-like 2) (RanBP2L2)
Gene: RGPD2

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Rab_bind~Ras, Ran_BP1~Ras
Common GO terms	GO:0005643 - nuclear pore GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1756 Hs			1 216
+	Hs
		483392 RGPD1_HUMAN (23-1756): 0: 2419: 99.83		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		919236 RGPD5_HUMAN (1-1751): 0: 2395: 93.41		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		152774 RGPD8_HUMAN (1-1750): 0: 2394: 93.46		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		919141 RGPD4_HUMAN (1-1748): 0: 2368: 95.34		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		63882 RGPD3_HUMAN (1-1748): 0: 2365: 94.94		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		914195 GCC2_HUMAN (1410-1751): 3.4e-71: 267: 40.45		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Ce
		184992 Q21021_CAEEL (913-1292): 1.72e-32: 139: 20.79		RAN_CAEEL (3-205): 3.44e-97: 283: 88.18
+	At
		784994 RBP1A_ARATH (1007-1232): 1.41e-36: 140: 26.75		RAN1_ARATH (1-216): 1.39e-95: 279: 73.52
+	At
		784989 RBP1B_ARATH (1003-1221): 6.79e-36: 138: 32.58		RAN1_ARATH (1-216): 1.39e-95: 279: 73.52
+	Hs
		919269 RANB3_HUMAN (793-1214): 3.15e-44: 172: 13.99		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Sp
		660086 RANG_SCHPO (943-1170): 1.56e-41: 154: 33.19		SPI1_SCHPO (1-214): 1.23e-84: 251: 80.84
+	At
		785000 RBP1A_ARATH (1007-1232): 1.41e-36: 140: 26.75		RAN2_ARATH (1-215): 1.36e-88: 261: 74.77
+	Hs
		834710 RBP2_HUMAN (793-1184): 2.02e-39: 163: 32.23		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	At
		784998 RBP1B_ARATH (1003-1221): 6.79e-36: 138: 32.58		RAN2_ARATH (1-215): 1.36e-88: 261: 74.77
+	At
		1210455 RBP1A_ARATH (1007-1232): 1.41e-36: 140: 26.75		RAN3_ARATH (1-215): 9.1e-84: 249: 74.31
+	Hs
		919306 NUP50_HUMAN (740-1162): 2.43e-37: 149: 15.47		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		796725 RANG_HUMAN (1007-1200): 9.43e-40: 148: 37.88		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Xl
		193796 O42193_XENLA (1007-1209): 7.54e-37: 140: 35.92		RAN_XENLA (1-216): 7.81e-80: 239: 98.15
+	Hs
		591920 GCC2_HUMAN (1410-1751): 3.4e-71: 267: 40.45		RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57
+	Hs
		845340 NUP50_HUMAN (740-1162): 2.43e-37: 149: 15.47		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13