HitPredict

Interactor 1: HS71A (P0DMV8)
Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 1) (HSP70-1) (HSP70.1) (Heat shock protein family A member 1A)
Gene: HSPA1A

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 815
+	Hs
		503749 HSP7C_HUMAN (1-613): 0: 984: 86.62		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Mm
		868987 HS71A_MOUSE (1-641): 0: 992: 95.32		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		561815 HS71L_MOUSE (3-641): 0: 991: 88.58		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		868875 HSP7C_MOUSE (1-613): 0: 984: 86.79		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		565421 HSP72_MOUSE (2-612): 0: 960: 84.83		ATX1_MOUSE (1-815): 0: 1271: 86.89