HitPredict

Interactor 1: HS71B (P0DMV9)
Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) (Heat shock protein family A member 1B)
Gene: HSPA1B

Interactor 2: TLE2 (Q04725)
Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2)
Gene: TLE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005925 - focal adhesion
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 743
+	Hs
		503942 HSP7C_HUMAN (1-613): 0: 984: 86.62		TLE2_HUMAN (1-743): 0: 552: 100.00
+	Hs
		871537 HSP72_HUMAN (2-641): 0: 964: 83.33		TLE2_HUMAN (1-743): 0: 552: 100.00
+	Hs
		503846 HSP7C_HUMAN (1-613): 0: 984: 86.62		GBB1_HUMAN (447-739): 3.21e-91: 290: 18.87
+	Hs
		920985 Q53FC7_HUMAN (6-641): 0: 982: 82.23		GBB1_HUMAN (447-739): 3.21e-91: 290: 18.87
+	Hs
		871524 HSP72_HUMAN (2-641): 0: 964: 83.33		GBB1_HUMAN (447-739): 3.21e-91: 290: 18.87
+	Hs
		503614 HSP7C_HUMAN (1-613): 0: 984: 86.62		LIS1_HUMAN (543-741): 6.74e-59: 206: 18.02
+	Hs
		503861 HSP7C_HUMAN (1-613): 0: 984: 86.62		RACK1_HUMAN (534-741): 2.3e-49: 178: 18.18
+	Hs
		503817 HSP7C_HUMAN (1-613): 0: 984: 86.62		WDR5_HUMAN (628-742): 1.63e-35: 139: 21.37
+	Hs
		504344 HSP7C_HUMAN (1-613): 0: 984: 86.62		WDR5B_HUMAN (627-742): 9.2e-34: 134: 22.03
+	Hs
		714020 HS71L_HUMAN (2-641): 0: 994: 89.06		POC1A_HUMAN (348-533): 2e-29: 123: 11.52
+	Hs
		564125 HSP76_HUMAN (6-641): 0: 988: 82.55		POC1A_HUMAN (348-533): 2e-29: 123: 11.52
+	Hs
		504412 HSP7C_HUMAN (1-613): 0: 984: 86.62		POC1A_HUMAN (348-533): 2e-29: 123: 11.52
+	Hs
		564054 HSP76_HUMAN (6-641): 0: 988: 82.55		GBB2_HUMAN (659-742): 3.82e-14: 76.4: 17.65
+	Hs
		483785 HS71B_HUMAN (1-641): 0: 987: 100.00		GBB2_HUMAN (659-742): 3.82e-14: 76.4: 17.65
+	Hs
		503848 HSP7C_HUMAN (1-613): 0: 984: 86.62		GBB2_HUMAN (659-742): 3.82e-14: 76.4: 17.65
+	Hs
		871525 HSP72_HUMAN (2-641): 0: 964: 83.33		GBB2_HUMAN (659-742): 3.82e-14: 76.4: 17.65