HitPredict

Interactor 1: HS71B (P0DMV9)
Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) (Heat shock protein family A member 1B)
Gene: HSPA1B

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2173
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 641 Hs			1 947
+	Hs
		714054 HS71L_HUMAN (2-641): 0: 994: 89.06		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Hs
		564159 HSP76_HUMAN (6-641): 0: 988: 82.55		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Mm
		926174 HSP7C_MOUSE (1-613): 0: 984: 86.79		M3K14_MOUSE (1-947): 0: 758: 83.98
+	Hs
		564016 HSP76_HUMAN (6-641): 0: 988: 82.55		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Hs
		503528 HSP7C_HUMAN (1-613): 0: 984: 86.62		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Rn
		483815 HS71B_RAT (1-641): 0: 997: 96.57		AAPK1_RAT (374-909): 5.75e-123: 386: 17.30
+	Hs
		504002 HSP7C_HUMAN (1-613): 0: 984: 86.62		AAPK1_HUMAN (374-909): 2.62e-124: 390: 17.48
+	Rn
		871238 HSP7C_RAT (1-613): 0: 984: 86.79		AAPK1_RAT (374-909): 5.75e-123: 386: 17.30
+	Hs
		713953 HS71L_HUMAN (2-641): 0: 994: 89.06		STK4_HUMAN (405-650): 2.6e-99: 321: 30.80
+	Hs
		564041 HSP76_HUMAN (6-641): 0: 988: 82.55		KS6A3_HUMAN (319-656): 2.54e-97: 324: 20.46
+	Hs
		564065 HSP76_HUMAN (6-641): 0: 988: 82.55		STK4_HUMAN (405-650): 2.6e-99: 321: 30.80
+	Hs
		503719 HSP7C_HUMAN (1-613): 0: 984: 86.62		KS6A3_HUMAN (319-656): 2.54e-97: 324: 20.46
+	Hs
		564080 HSP76_HUMAN (6-641): 0: 988: 82.55		KS6A1_HUMAN (319-695): 1.9e-95: 318: 18.21
+	Hs
		503996 HSP7C_HUMAN (1-613): 0: 984: 86.62		STK4_HUMAN (405-650): 2.6e-99: 321: 30.80
+	Hs
		713919 HS71L_HUMAN (2-641): 0: 994: 89.06		M3K8_HUMAN (379-647): 2.68e-29: 124: 30.66
+	Hs
		503599 HSP7C_HUMAN (1-613): 0: 984: 86.62		M3K8_HUMAN (379-647): 2.68e-29: 124: 30.66
+	Hs
		713957 HS71L_HUMAN (2-641): 0: 994: 89.06		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		564068 HSP76_HUMAN (6-641): 0: 988: 82.55		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		714056 HS71L_HUMAN (2-641): 0: 994: 89.06		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		564164 HSP76_HUMAN (6-641): 0: 988: 82.55		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14