HitPredict

Interactor 1: HS71B (P0DMV9)
Heat shock 70 kDa protein 1B (Heat shock 70 kDa protein 2) (HSP70-2) (HSP70.2) (Heat shock protein family A member 1B)
Gene: HSPA1B

Interactor 2: HPBP1 (Q9NZL4)
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Gene: HSPBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0031625 - ubiquitin protein ligase binding GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 359
+	Hs
		714085 HS71L_HUMAN (2-641): 0: 994: 89.06		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		564199 HSP76_HUMAN (6-641): 0: 988: 82.55		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		504872 HSP7C_HUMAN (1-613): 0: 984: 86.62		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		871809 HSP72_HUMAN (2-641): 0: 964: 83.33		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Dm
		947885 HSP70_DROME (6-641): 0: 944: 74.23		Q95RI2_DROME (39-344): 2.79e-63: 205: 22.26
+	Hs
		134830 HSP7C_HUMAN (1-613): 0: 984: 86.62		IMA3_HUMAN (57-331): 3.72e-21: 96.5: 14.39