HitPredict

Interactor 1: CALM2 (P0DP24)
Calmodulin-2
Gene: CALM2

Interactor 2: KCC2G (Q13555)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: CAMK2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 149 Hs			1 558
+	Hs
		483927 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		484119 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Hs
		648497 CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56		KCC2G_HUMAN (1-558): 0: 672: 100.00
+	Dm
		825619 CALL_DROME (3-149): 9.23e-57: 175: 66.67		KCC2A_DROME (1-552): 0: 574: 67.94
+	Dm
		906661 CALM_DROME (1-149): 5.63e-56: 173: 97.99		KCC2A_DROME (1-552): 0: 574: 67.94
+	Hs
		483928 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		484002 CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		484120 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2D_HUMAN (1-558): 0: 525: 64.88
+	Hs
		483929 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC1A_HUMAN (6-336): 4.19e-138: 406: 37.76
+	Hs
		483947 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC1D_HUMAN (2-315): 8.38e-138: 406: 38.80
+	Ce
		183804 CALM_CAEEL (1-149): 2.09e-55: 172: 97.99		CMK1_CAEEL (2-339): 7.85e-138: 405: 38.05
+	At
		483086 CALM4_ARATH (1-149): 1.59e-53: 167: 89.26		CDPK3_ARATH (14-332): 9.72e-137: 408: 32.71
+	At
		886549 CALM7_ARATH (1-149): 1.98e-53: 167: 89.93		CDPK3_ARATH (14-332): 9.72e-137: 408: 32.71
+	At
		976625 CALM6_ARATH (1-149): 2.84e-53: 166: 89.26		CDPK3_ARATH (14-332): 9.72e-137: 408: 32.71
+	Hs
		648500 CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56		KCC1A_HUMAN (6-336): 4.19e-138: 406: 37.76
+	Hs
		648542 CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56		KCC1D_HUMAN (2-315): 8.38e-138: 406: 38.80
+	Dm
		906677 CALM_DROME (1-149): 5.63e-56: 173: 97.99		Q7JMV3_DROME (12-312): 4.09e-70: 232: 41.51
+	Hs
		483926 CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Hs
		484000 CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29
+	Hs
		484118 CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00		KCC2B_HUMAN (287-558): 1.59e-57: 205: 49.29