HitPredict

Interactor 1: RPAC2 (P0DPB6)
DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19)
Gene: POLR1D

Interactor 2: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	35271311, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0001056 - RNA polymerase III activity GO:0003677 - DNA binding GO:0005666 - RNA polymerase III complex GO:0005736 - RNA polymerase I complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 67
+	Hs
		854410 RPB11_HUMAN (18-123): 1.18e-41: 135: 31.13		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Hs
		921160 RPB1B_HUMAN (18-118): 6.29e-39: 128: 29.70		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Sc
		604657 RPAC2_YEAST (1-119): 1.44e-39: 131: 45.38		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Sc
		604679 RPB11_YEAST (18-117): 5.94e-35: 119: 28.00		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06