HitPredict

Interactor 1: NT2NC (P0DPK4)
Notch homolog 2 N-terminal-like protein C
Gene: NOTCH2NLC

Interactor 2: KRA59 (P26371)
Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Gene: KRTAP5-9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 293 Hs			1 169
+	Hs
		484586 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR10A_HUMAN (3-166): 1.8e-20: 86.7: 27.00
+	Hs
		642099 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		KRA59_HUMAN (1-169): 2.65e-53: 168: 100.00
+	Hs
		484591 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR109_HUMAN (39-168): 9.93e-17: 77.1: 26.14
+	Hs
		484589 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR105_HUMAN (6-165): 3.51e-16: 75.5: 26.06
+	Hs
		484590 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87
+	Hs
		484702 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KRA92_HUMAN (47-166): 3.82e-14: 68.2: 34.71
+	Hs
		484701 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KRA93_HUMAN (63-166): 1.18e-12: 64: 29.81
+	Hs
		484703 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR411_HUMAN (1-131): 4.08e-12: 63.2: 25.19
+	Hs
		484704 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KRA45_HUMAN (7-160): 5.89e-12: 62.4: 26.04
+	Hs
		484705 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KRA44_HUMAN (1-127): 4.34e-12: 62.4: 29.13
+	Hs
		484700 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KRA98_HUMAN (52-167): 1.94e-11: 60.5: 35.04
+	Hs
		484585 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR122_HUMAN (54-166): 4.13e-10: 57: 29.20
+	Hs
		484584 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR121_HUMAN (38-127): 2.72e-10: 56.2: 23.08
+	Hs
		484706 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KRA42_HUMAN (11-107): 9.97e-10: 55.5: 24.24
+	Hs
		484587 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		KR123_HUMAN (6-98): 8.5e-10: 54.7: 23.16
+	Dm
		247183 Q9VTP0_DROME (2-167): 5.08e-24: 103: 25.95		TENM_DROME (47-168): 1.59e-09: 57.8: 20.80
+	Hs
		887741 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		KR10A_HUMAN (3-166): 1.8e-20: 86.7: 27.00
+	Hs
		887386 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		KR122_HUMAN (54-166): 4.13e-10: 57: 29.20
+	Hs
		887326 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		KR121_HUMAN (38-127): 2.72e-10: 56.2: 23.08
+	Hs
		888574 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		KR123_HUMAN (6-98): 8.5e-10: 54.7: 23.16