HitPredict

Interactor 1: NT2NC (P0DPK4)
Notch homolog 2 N-terminal-like protein C
Gene: NOTCH2NLC

Interactor 2: BCAM (P50895)
Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239)
Gene: BCAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EGF~V-set
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 293 Hs			1 628
+	Hs
		842264 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		BCAM_HUMAN (1-610): 3.86e-97: 312: 100.00
+	Hs
		793285 NOTC2_HUMAN (5-241): 2.39e-09: 60.1: 21.81		MUC18_HUMAN (14-627): 1.18e-81: 271: 24.02
+	Hs
		296682 SLIT2_HUMAN (43-170): 1.65e-10: 63.5: 24.62		ROBO1_HUMAN (1-454): 7.56e-58: 213: 14.08
+	Hs
		484602 NT2NC_HUMAN (1-293): 1.76e-48: 164: 100.00		PTK7_HUMAN (449-628): 5.81e-18: 90.5: 11.64
+	Hs
		804225 NOTC1_HUMAN (6-165): 1.83e-14: 75.8: 30.49		CNTN1_HUMAN (6-604): 7.07e-43: 167: 12.82
+	Hs
		980365 NOTC2_HUMAN (5-241): 2.39e-09: 60.1: 21.81		CNTN1_HUMAN (6-604): 7.07e-43: 167: 12.82
+	Dm
		422809 NOTCH_DROME (8-205): 3.93e-09: 59.7: 19.74		Q9BN17_DROME (7-543): 6.27e-42: 165: 15.39
+	Hs
		980481 NOTC2_HUMAN (5-241): 2.39e-09: 60.1: 21.81		PXDN_HUMAN (12-356): 7.19e-37: 150: 21.17
+	Dr
		65452 Q9DE36_DANRE (39-166): 3.01e-10: 62.8: 25.39		A8DZ85_DANRE (351-627): 3.85e-36: 147: 15.83
+	Dr
		65450 Q3Y6S4_DANRE (8-207): 1.83e-09: 60.5: 19.12		A8DZ85_DANRE (351-627): 3.85e-36: 147: 15.83
+	Dm
		219803 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		O44924_DROME (452-625): 9.38e-21: 99.4: 13.16
+	Dm
		621597 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9W213_DROME (452-625): 9.14e-21: 99.4: 13.16
+	Dr
		1265014 Q9DE36_DANRE (39-166): 3.01e-10: 62.8: 25.39		Q90Z70_DANRE (451-627): 5.63e-26: 115: 16.49
+	Dm
		621596 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9VQ08_DROME (10-289): 1.18e-12: 73.5: 18.24
+	Dm
		621592 SLIT_DROME (13-162): 2.9e-24: 104: 23.90		Q9GPP7_DROME (10-289): 1.5e-12: 73.1: 18.24
+	Hs
		1031145 NT2NA_HUMAN (22-229): 8.21e-15: 73.9: 30.37		PTK7_HUMAN (449-628): 5.81e-18: 90.5: 11.64
+	Ce
		103935 SLIT1_CAEEL (202-281): 5.31e-12: 68.1: 25.93		SAX3_CAEEL (444-627): 1.17e-19: 95.9: 14.14
+	Dm
		246777 TENM_DROME (2-103): 9.19e-10: 61.6: 14.73		DSCA1_DROME (9-623): 1.64e-16: 85.9: 8.19
+	Mm
		1112695 TEN4_MOUSE (2-106): 7.07e-10: 62: 13.97		PTK7_MOUSE (6-159): 2.12e-15: 82: 16.05
+	Dm
		422964 NOTCH_DROME (8-205): 3.93e-09: 59.7: 19.74		Q9W4Y4_DROME (283-485): 2.52e-11: 69.3: 26.85