Interactor 1: SPIKE (P0DTC2)
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
Gene: S
Interactor 2: SPIKE (P0DTC2)
Spike glycoprotein (S glycoprotein) (E2) (Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2']
Gene: S
Species: Severe acute respiratory syndrome coronavirus 2
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.99 | 1.00 | 0.999 |
The method score is based on:
Property | Details |
---|---|
Experiments | 32075877, 32155444, 888800000035, 33845483, 32887876, 32703908, 32661423, 32841605, 32805734, 32991842, 888800000079, 33154106, 34015061, 888800000094, 33128388, 33556147, 33177651, 32907861, 888800000150, 33731853 and 233 others
more... |
Identification Methods | x-ray crystallography, pull down, affinity chromatography technology, biochemical, proximity labelling technology, protein complementation assay, fluorescent resonance energy transfer, 3D electron microscopy, electron tomography, molecular sieving and 12 others
more... |
Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | bCoV_S1_N~bCoV_S1_N, bCoV_S1_N~bCoV_S1_RBD, CoV_S1_C~bCoV_S1_N, CoV_S2~bCoV_S1_N, bCoV_S1_RBD~bCoV_S1_RBD, CoV_S1_C~bCoV_S1_RBD, CoV_S2~bCoV_S1_RBD, CoV_S1_C~CoV_S2, CoV_S2~CoV_S2 |
Common GO terms | GO:0005886 - plasma membrane GO:0016020 - membrane GO:0019031 - viral envelope GO:0019062 - virion attachment to host cell GO:0019064 - fusion of virus membrane with host plasma membrane and 16 others more... |
Homologous interactions | 1 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024