Interactor 1: VME1 (P0DTC5)
Membrane protein (M) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)
Gene: M

Interactor 2: VME1 (P0DTC5)
Membrane protein (M) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)
Gene: M

Species: Severe acute respiratory syndrome coronavirus 2

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 32838362, 34709727, 35100873, 36264056, 34672954, 34671206, 888800000946, 888800001031
Identification Methods affinity chromatography technology, proximity labelling technology, x-ray crystallography, biochemical, pull down, protein complementation assay, fluorescent resonance energy transfer, bimolecular fluorescence complementation, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 - plasma membrane
GO:0019031 - viral envelope
GO:0019049 - virus-mediated perturbation of host defense response
GO:0039545 - symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 222
Sa

1 222
+ Sa

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024