HitPredict

Interactor 1: GLI2 (P10070)
Zinc finger protein GLI2 (GLI family zinc finger protein 2) (Tax helper protein)
Gene: GLI2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27477274
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1586 Hs			1 768
+	Hs
		1042144 ZN480_HUMAN (327-732): 1.01e-127: 410: 19.22		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		983757 ZNF91_HUMAN (531-1449): 6e-114: 391: 6.94		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042045 ZN615_HUMAN (578-1025): 4.92e-102: 346: 6.77		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042050 ZN565_HUMAN (294-663): 1.04e-98: 330: 21.45		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		73009 ZN879_HUMAN (408-732): 1.11e-95: 322: 21.18		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Dm
		585743 CI_DROME (78-1117): 9.86e-112: 389: 28.52		Q8IP45_DROME (17-768): 0: 868: 69.08
+	Hs
		1042051 ZN383_HUMAN (361-666): 2e-85: 290: 23.86		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042615 ZN331_HUMAN (462-664): 2.05e-78: 269: 28.08		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042316 ZN582_HUMAN (359-666): 5.13e-77: 267: 24.19		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041958 ZN761_HUMAN (544-968): 3.12e-60: 224: 10.63		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041826 Z585A_HUMAN (672-1362): 6.85e-57: 214: 5.69		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041764 ZN658_HUMAN (554-1449): 4.37e-55: 212: 7.07		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041578 ZN268_HUMAN (647-1443): 9.14e-54: 207: 7.01		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		73014 B4DU56_HUMAN (80-410): 2.38e-51: 194: 8.24		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		988832 ZN33B_HUMAN (81-383): 7.04e-46: 180: 7.74		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042799 ZN229_HUMAN (676-1335): 1.2e-34: 146: 7.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042028 ZN808_HUMAN (744-1450): 8.99e-34: 143: 7.57		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Dm
		585713 CI_DROME (78-1117): 9.86e-112: 389: 28.52		CUL1_DROME (29-768): 0: 669: 27.49
+	Hs
		1043522 ZN582_HUMAN (359-666): 5.13e-77: 267: 24.19		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Ce
		712866 TRA1_CAEEL (435-599): 2.51e-51: 200: 58.93		CUL2_CAEEL (30-768): 0: 613: 24.10