HitPredict

Interactor 1: TZAP (P10074)
Telomere zinc finger-associated protein (TZAP) (Krueppel-related zinc finger protein 3) (hKR3) (Zinc finger and BTB domain-containing protein 48) (Zinc finger protein 855)
Gene: ZBTB48

Interactor 2: NSD1 (Q96L73)
Histone-lysine N-methyltransferase, H3 lysine-36 specific (EC 2.1.1.357) (Androgen receptor coactivator 267 kDa protein) (Androgen receptor-associated protein of 267 kDa) (H3-K36-HMTase) (Lysine N-methyltransferase 3B) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein)
Gene: NSD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 688 Hs			1 2696
+	Hs
		485245 TZAP_HUMAN (1-688): 0: 639: 100.00		EZH2_HUMAN (1883-2067): 7.8e-59: 220: 29.80
+	Hs
		850257 ZN157_HUMAN (472-600): 1.27e-11: 69.7: 31.78		EZH2_HUMAN (1883-2067): 7.8e-59: 220: 29.80