HitPredict

Interactor 1: AST5 (P10083)
Achaete-scute complex protein T5 (Protein achaete)
Gene: ac

Interactor 2: ESM8 (P13098)
Enhancer of split m8 protein (E(spl)m8)
Gene: E(spl)m8-HLH

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0043565 - sequence-specific DNA binding GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 201 Dm			1 179
+	Dm
		485892 AST5_DROME (1-201): 2.69e-67: 206: 100.00		ESMB_DROME (3-179): 5.04e-56: 176: 35.26
+	Dm
		485886 AST5_DROME (1-201): 2.69e-67: 206: 100.00		ESM7_DROME (3-179): 8.96e-52: 165: 40.86
+	Dm
		485893 AST5_DROME (1-201): 2.69e-67: 206: 100.00		ESMC_DROME (1-179): 4.11e-51: 164: 35.00
+	Dm
		485885 AST5_DROME (1-201): 2.69e-67: 206: 100.00		ESM5_DROME (2-179): 1.52e-46: 152: 60.00
+	Dm
		485891 AST5_DROME (1-201): 2.69e-67: 206: 100.00		ESM3_DROME (3-179): 3.86e-44: 147: 24.78
+	Dm
		485919 AST4_DROME (22-199): 9.02e-40: 140: 32.67		ESM8_DROME (1-179): 1.11e-61: 190: 100.00
+	Dm
		485926 AST4_DROME (22-199): 9.02e-40: 140: 32.67		ESMB_DROME (3-179): 5.04e-56: 176: 35.26
+	Dm
		485918 AST4_DROME (22-199): 9.02e-40: 140: 32.67		ESM7_DROME (3-179): 8.96e-52: 165: 40.86
+	Dm
		485927 AST4_DROME (22-199): 9.02e-40: 140: 32.67		ESMC_DROME (1-179): 4.11e-51: 164: 35.00
+	Dm
		485917 AST4_DROME (22-199): 9.02e-40: 140: 32.67		ESM5_DROME (2-179): 1.52e-46: 152: 60.00
+	Dm
		485925 AST4_DROME (22-199): 9.02e-40: 140: 32.67		ESM3_DROME (3-179): 3.86e-44: 147: 24.78
+	Dm
		454872 AST8_DROME (23-115): 1.32e-18: 84.7: 49.46		ESMB_DROME (3-179): 5.04e-56: 176: 35.26
+	Dm
		525745 ATO_DROME (19-94): 1.78e-12: 66.6: 31.25		ESM8_DROME (1-179): 1.11e-61: 190: 100.00
+	Dm
		454869 AST8_DROME (23-115): 1.32e-18: 84.7: 49.46		ESM7_DROME (3-179): 8.96e-52: 165: 40.86
+	Dm
		454873 AST8_DROME (23-115): 1.32e-18: 84.7: 49.46		ESMC_DROME (1-179): 4.11e-51: 164: 35.00
+	Dm
		454871 AST8_DROME (23-115): 1.32e-18: 84.7: 49.46		ESM3_DROME (3-179): 3.86e-44: 147: 24.78
+	Dm
		525719 ATO_DROME (19-94): 1.78e-12: 66.6: 31.25		ESM7_DROME (3-179): 8.96e-52: 165: 40.86
+	Rn
		583274 ASCL1_RAT (17-176): 1.76e-22: 92.4: 30.00		HES5_RAT (3-179): 1.37e-38: 131: 18.54
+	Dm
		823151 ATO_DROME (19-94): 1.78e-12: 66.6: 31.25		ESM3_DROME (3-179): 3.86e-44: 147: 24.78
+	Mm
		485959 MYOD1_MOUSE (17-180): 4.32e-21: 90.5: 18.18		BHE41_MOUSE (7-133): 5.31e-30: 114: 20.28