HitPredict

Interactor 1: AST5 (P10083)
Achaete-scute complex protein T5 (Protein achaete)
Gene: ac

Interactor 2: EMC (P18491)
Protein extra-macrochaetae
Gene: EMC

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.864

Property	Details
Experiments	7821225, 25977368, 9371806, unassigned4
Identification Methods	affinity chromatography technology, two hybrid, experimental interaction detection
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0008407 - chaeta morphogenesis GO:0046982 - protein heterodimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 201 Dm			1 199
+	Dm
		485922 AST4_DROME (22-199): 9.02e-40: 140: 32.67		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		454857 AST3_DROME (34-199): 3.89e-39: 136: 38.82		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		454870 AST8_DROME (23-115): 1.32e-18: 84.7: 49.46		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Hs
		526742 MYF5_HUMAN (25-185): 1.96e-28: 108: 18.01		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		568188 TAL1_HUMAN (12-187): 4.39e-23: 95.9: 19.44		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		780971 ASCL4_HUMAN (19-118): 4.22e-25: 97.8: 32.00		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		526743 MYF5_HUMAN (25-185): 1.96e-28: 108: 18.01		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Hs
		814914 ASCL3_HUMAN (20-117): 5.72e-22: 90.1: 29.59		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		524549 LYL1_HUMAN (8-152): 4.28e-21: 89.7: 16.89		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Mm
		589139 TAL1_MOUSE (12-180): 1.34e-22: 94.7: 19.65		ID1_MOUSE (38-99): 5.12e-29: 107: 47.76
+	Mm
		485951 MYOD1_MOUSE (17-180): 4.32e-21: 90.5: 18.18		Q6GTZ3_MOUSE (38-99): 8.25e-29: 106: 47.76
+	Hs
		780989 ASCL3_HUMAN (20-117): 5.72e-22: 90.1: 29.59		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		524547 LYL1_HUMAN (8-152): 4.28e-21: 89.7: 16.89		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		970583 ASCL4_HUMAN (19-118): 4.22e-25: 97.8: 32.00		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Hs
		526744 MYF5_HUMAN (25-185): 1.96e-28: 108: 18.01		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67
+	Mm
		485939 MYOD1_MOUSE (17-180): 4.32e-21: 90.5: 18.18		ID2_MOUSE (38-103): 5.4e-25: 96.4: 43.06
+	Mm
		485938 MYOD1_MOUSE (17-180): 4.32e-21: 90.5: 18.18		ID3_MOUSE (38-97): 1.05e-19: 82.1: 36.67
+	Hs
		524557 LYL1_HUMAN (8-152): 4.28e-21: 89.7: 16.89		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67