HitPredict

Interactor 1: AST4 (P10084)
Achaete-scute complex protein T4 (Protein scute)
Gene: sc

Interactor 2: EMC (P18491)
Protein extra-macrochaetae
Gene: EMC

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.947

Property	Details
Experiments	7821225, 30995488, 9371806, 9524128, 14605208, unassigned4
Identification Methods	affinity chromatography technology, two hybrid, pull down, two hybrid array, miniaturized immunoprecipitation, experimental interaction detection
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0007530 - sex determination GO:0008407 - chaeta morphogenesis GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 345 Dm			1 199
+	Dm
		454857 AST3_DROME (76-345): 6.61e-38: 137: 35.56		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		454870 AST8_DROME (62-272): 6.16e-33: 129: 29.52		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		485888 AST5_DROME (72-170): 3.57e-24: 99.8: 52.94		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Hs
		524549 LYL1_HUMAN (17-234): 2.85e-27: 110: 18.86		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Mm
		485951 MYOD1_MOUSE (40-226): 2.27e-29: 116: 17.65		Q6GTZ3_MOUSE (38-99): 8.25e-29: 106: 47.76
+	Hs
		780971 ASCL4_HUMAN (41-197): 2.16e-30: 115: 29.52		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		814914 ASCL3_HUMAN (49-181): 4.4e-27: 107: 28.17		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		616610 MYF6_HUMAN (37-213): 3.31e-26: 106: 20.43		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		524547 LYL1_HUMAN (17-234): 2.85e-27: 110: 18.86		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		568188 TAL1_HUMAN (52-225): 3.21e-23: 100: 20.21		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		780989 ASCL3_HUMAN (49-181): 4.4e-27: 107: 28.17		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Mm
		485939 MYOD1_MOUSE (40-226): 2.27e-29: 116: 17.65		ID2_MOUSE (38-103): 5.4e-25: 96.4: 43.06
+	Hs
		814916 NGN3_HUMAN (26-228): 1.69e-23: 98.2: 15.49		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		970583 ASCL4_HUMAN (41-197): 2.16e-30: 115: 29.52		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Mm
		589139 TAL1_MOUSE (52-225): 8.54e-23: 99: 20.97		ID1_MOUSE (38-99): 5.12e-29: 107: 47.76
+	Hs
		545945 MYOD1_HUMAN (40-221): 5.55e-23: 99.4: 17.58		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Mm
		485938 MYOD1_MOUSE (40-226): 2.27e-29: 116: 17.65		ID3_MOUSE (38-97): 1.05e-19: 82.1: 36.67
+	Hs
		545958 MYOD1_HUMAN (40-221): 5.55e-23: 99.4: 17.58		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Hs
		524557 LYL1_HUMAN (17-234): 2.85e-27: 110: 18.86		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67
+	Hs
		545959 MYOD1_HUMAN (40-221): 5.55e-23: 99.4: 17.58		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67