HitPredict - High confidence protein-protein interactions

Interactor 1: MYOD1 (P10085)
Myoblast determination protein 1
Gene: MYOD1

Interactor 2: SMAD3 (Q8BUN5)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)
Gene: SMAD3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	20211142, 11711431, 22036565
Identification Methods	two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000987 - cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific and 16 others more... GO:0003682 - chromatin binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0005737 - cytoplasm GO:0019899 - enzyme binding GO:0031490 - chromatin DNA binding GO:0031625 - ubiquitin protein ligase binding GO:0042803 - protein homodimerization activity GO:0043425 - bHLH transcription factor binding GO:0043565 - sequence-specific DNA binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:1990841 - promoter-specific chromatin binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	318
Mm

1	425

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Last updated: 15 Jul 2024