HitPredict

Interactor 1: RAP2A (P10114)
Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30)
Gene: RAP2A

Interactor 2: RB40B (Q12829)
Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar)
Gene: RAB40B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	35293963
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0072659 - protein localization to plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 278
+	Hs
		897980 RAP2B_HUMAN (1-182): 2.01e-82: 243: 91.21		RB40B_HUMAN (1-278): 4.13e-106: 311: 100.00
+	Hs
		1017285 RAP2C_HUMAN (1-183): 2.97e-81: 240: 91.26		RB40B_HUMAN (1-278): 4.13e-106: 311: 100.00
+	Xl
		1140166 Q7ZX67_XENLA (16-183): 1.44e-78: 233: 98.81		Q5XHF6_XENLA (1-278): 6.53e-97: 287: 77.62
+	Zm
		73944 B4FAE1_MAIZE (4-178): 1.03e-79: 237: 36.36		B4FAE1_MAIZE (7-198): 3.25e-92: 272: 36.95
+	Hs
		918846 RAB1A_HUMAN (4-183): 5.73e-80: 238: 34.25		RAB1A_HUMAN (4-197): 1.54e-89: 266: 38.05
+	Dm
		185469 RAP1_DROME (1-165): 8.23e-81: 239: 64.24		O18332_DROME (4-197): 5.86e-88: 262: 36.59
+	Hs
		918944 RAB1A_HUMAN (4-183): 5.73e-80: 238: 34.25		RAB1B_HUMAN (7-197): 1.37e-86: 258: 36.82
+	Mm
		919000 RAB1A_MOUSE (4-183): 5.73e-80: 238: 34.25		RAB1B_MOUSE (7-197): 2.66e-86: 257: 37.31
+	Hs
		913992 RAB1A_HUMAN (4-183): 5.73e-80: 238: 34.25		RB11A_HUMAN (4-215): 1.01e-85: 256: 30.52
+	Hs
		918879 RAB1A_HUMAN (4-183): 5.73e-80: 238: 34.25		RB11B_HUMAN (4-216): 3.79e-85: 255: 31.16
+	Hs
		918916 RAB1A_HUMAN (4-183): 5.73e-80: 238: 34.25		RAB2B_HUMAN (10-230): 1.09e-84: 254: 27.03
+	Hs
		897876 RAP1B_HUMAN (1-182): 4.24e-79: 234: 60.66		RB11A_HUMAN (4-215): 1.01e-85: 256: 30.52
+	Mm
		914510 RB11A_MOUSE (4-179): 4.34e-77: 231: 30.51		RB11A_MOUSE (4-215): 1.01e-85: 256: 30.52
+	Hs
		1079964 RAB1B_HUMAN (4-178): 1.24e-76: 229: 34.09		RB11B_HUMAN (4-216): 3.79e-85: 255: 31.16
+	Hs
		1259991 RAB1B_HUMAN (4-178): 1.24e-76: 229: 34.09		RAB2B_HUMAN (10-230): 1.09e-84: 254: 27.03
+	Hs
		895549 RAB1B_HUMAN (4-178): 1.24e-76: 229: 34.09		RAB10_HUMAN (9-197): 3.44e-84: 252: 40.10
+	Hs
		845881 RAB1B_HUMAN (4-178): 1.24e-76: 229: 34.09		RAB13_HUMAN (7-197): 7.91e-84: 251: 42.19
+	Hs
		894715 RAB1A_HUMAN (4-183): 5.73e-80: 238: 34.25		RAB8A_HUMAN (9-172): 1.01e-46: 157: 47.27
+	Mm
		918981 RAB1A_MOUSE (4-183): 5.73e-80: 238: 34.25		Q3TYB1_MOUSE (9-195): 2.21e-46: 156: 43.98