Interactor 1: GRAB (P10144)
Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E)
Gene: GZMB

Interactor 2: PERF (P14222)
Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Gene: PRF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 11911826
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001772 - immunological synapse
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0016020 - membrane
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 247
Hs

1 555
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024