HitPredict

Interactor 1: CCL1 (P10146)
C-C motif chemokine 1 (P500) (SIS-epsilon) (Small-inducible cytokine A1) (T-cell activation protein 3) (TCA-3) (TCA3)
Gene: CCL1

Interactor 2: CCR8 (P56484)
C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CD antigen CDw198)
Gene: CCR8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	34407391
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 92 Mm			1 353
+	Hs
		561732 CL3L1_HUMAN (1-90): 1.21e-31: 107: 27.47		CCR3_HUMAN (12-346): 2.88e-88: 271: 37.65
+	Hs
		486237 CCL3_HUMAN (1-90): 3.89e-31: 106: 24.44		CCR3_HUMAN (12-346): 2.88e-88: 271: 37.65
+	Hs
		526564 CCL4_HUMAN (1-90): 2.29e-30: 104: 27.47		CCR3_HUMAN (12-346): 2.88e-88: 271: 37.65
+	Hs
		134354 CCL3_HUMAN (1-90): 3.89e-31: 106: 24.44		ACKR2_HUMAN (6-313): 3.37e-81: 253: 36.89
+	Hs
		134356 CCL4_HUMAN (1-90): 2.29e-30: 104: 27.47		ACKR2_HUMAN (6-313): 3.37e-81: 253: 36.89
+	Hs
		134373 CCL8_HUMAN (15-90): 8.28e-30: 103: 21.05		ACKR2_HUMAN (6-313): 3.37e-81: 253: 36.89
+	Mm
		486358 CCL2_MOUSE (1-90): 8.54e-31: 107: 28.57		CCR2_MOUSE (12-344): 7.17e-78: 245: 41.02
+	Hs
		486238 CCL3_HUMAN (1-90): 3.89e-31: 106: 24.44		CCR4_HUMAN (2-353): 1.17e-77: 244: 41.36
+	Mm
		500591 CCL3_MOUSE (1-90): 3.48e-30: 104: 27.47		CCR3_MOUSE (11-343): 2.36e-78: 245: 39.10
+	Hs
		561728 CL3L1_HUMAN (1-90): 1.21e-31: 107: 27.47		CCR1_HUMAN (20-343): 1.79e-76: 240: 40.49
+	Hs
		486230 CCL3_HUMAN (1-90): 3.89e-31: 106: 24.44		CCR1_HUMAN (20-343): 1.79e-76: 240: 40.49
+	Hs
		526560 CCL4_HUMAN (1-90): 2.29e-30: 104: 27.47		CCR1_HUMAN (20-343): 1.79e-76: 240: 40.49
+	Hs
		686635 CCL8_HUMAN (15-90): 8.28e-30: 103: 21.05		CCR1_HUMAN (20-343): 1.79e-76: 240: 40.49
+	Hs
		561733 CL3L1_HUMAN (1-90): 1.21e-31: 107: 27.47		CCR5_HUMAN (1-344): 5.25e-71: 226: 41.91
+	Hs
		486239 CCL3_HUMAN (1-90): 3.89e-31: 106: 24.44		CCR5_HUMAN (1-344): 5.25e-71: 226: 41.91
+	Hs
		526565 CCL4_HUMAN (1-90): 2.29e-30: 104: 27.47		CCR5_HUMAN (1-344): 5.25e-71: 226: 41.91
+	Mm
		500590 CCL3_MOUSE (1-90): 3.48e-30: 104: 27.47		CCR1_MOUSE (2-343): 1.01e-69: 223: 37.79
+	Mm
		139696 CCL2_MOUSE (1-90): 8.54e-31: 107: 28.57		ACKR2_MOUSE (13-309): 2.29e-53: 181: 38.59
+	Hs
		486231 CCL3_HUMAN (1-90): 3.89e-31: 106: 24.44		CXCR5_HUMAN (34-315): 3.62e-40: 147: 31.60
+	Hs
		526561 CCL4_HUMAN (1-90): 2.29e-30: 104: 27.47		CXCR5_HUMAN (34-315): 3.62e-40: 147: 31.60