HitPredict

Interactor 1: CCL3 (P10147)
C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))]
Gene: CCL3

Interactor 2: LAMA1 (P25391)
Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)
Gene: LAMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 3075
+	Hs
		433113 CCL3_HUMAN (1-92): 2.25e-36: 119: 100.00		LAMB1_HUMAN (221-555): 7.05e-30: 133: 20.29
+	Hs
		317783 CCL3_HUMAN (1-92): 2.25e-36: 119: 100.00		NET1_HUMAN (848-987): 2.68e-14: 81.2: 27.95
+	Hs
		317785 CL3L1_HUMAN (1-92): 2.12e-35: 117: 94.62		NET1_HUMAN (848-987): 2.68e-14: 81.2: 27.95
+	Hs
		486215 CCL3_HUMAN (1-92): 2.25e-36: 119: 100.00		LAMC1_HUMAN (1247-1464): 2.01e-10: 69.2: 17.70
+	Hs
		486264 CCL3_HUMAN (1-92): 2.25e-36: 119: 100.00		LAMA4_HUMAN (483-664): 7.04e-10: 67.3: 10.09
+	Hs
		486243 CCL3_HUMAN (1-92): 2.25e-36: 119: 100.00		LAMB2_HUMAN (1149-1439): 1.33e-09: 66.5: 11.57
+	Hs
		172638 CCL3_HUMAN (1-92): 2.25e-36: 119: 100.00		LAMA5_HUMAN (485-755): 2.42e-09: 65.8: 9.96
+	Hs
		172643 CL3L1_HUMAN (1-92): 2.12e-35: 117: 94.62		LAMA5_HUMAN (485-755): 2.42e-09: 65.8: 9.96