HitPredict

Interactor 1: MYB (P10242)
Transcriptional activator Myb (Proto-oncogene c-Myb)
Gene: MYB

Interactor 2: MYB (P10242)
Transcriptional activator Myb (Proto-oncogene c-Myb)
Gene: MYB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

The method score is based on:

Property	Details
Experiments	18093978
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Myb_DNA-binding~Myb_DNA-binding
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000278 - mitotic cell cycle GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific and 28 others more... GO:0001666 - response to hypoxia GO:0002931 - response to ischemia GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription GO:0014856 - skeletal muscle cell proliferation GO:0016363 - nuclear matrix GO:0030218 - erythrocyte differentiation GO:0032967 - positive regulation of collagen biosynthetic process GO:0043525 - positive regulation of neuron apoptotic process GO:0045064 - T-helper 2 cell differentiation GO:0045653 - negative regulation of megakaryocyte differentiation GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048661 - positive regulation of smooth muscle cell proliferation GO:0060252 - positive regulation of glial cell proliferation GO:0061515 - myeloid cell development GO:0070301 - cellular response to hydrogen peroxide GO:0071300 - cellular response to retinoic acid GO:0071636 - positive regulation of transforming growth factor beta production GO:0090575 - RNA polymerase II transcription regulator complex GO:1901533 - negative regulation of hematopoietic progenitor cell differentiation GO:1902895 - positive regulation of miRNA transcription GO:1904899 - positive regulation of hepatic stellate cell proliferation GO:2000491 - positive regulation of hepatic stellate cell activation GO:2000845 - positive regulation of testosterone secretion
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	640
Hs

1	640

+

Hs

+

Hs

+

Sp

+

At

+

Sc

+

At

+

At

+

At

+

Zm

+

At

+

At

+

At

+

At

+

At

+

At

+

At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024